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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC135
All Species:
25.15
Human Site:
Y480
Identified Species:
55.33
UniProt:
Q8IY82
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY82
NP_115645.4
874
103497
Y480
I
L
E
I
K
E
W
Y
Q
N
R
E
D
M
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100628
830
97575
Y480
I
L
E
I
K
E
W
Y
Q
N
R
E
D
M
L
Dog
Lupus familis
XP_544386
903
106348
Y509
T
L
E
I
K
E
W
Y
Q
N
R
E
D
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6V3W6
876
103192
Y482
V
L
E
I
K
E
W
Y
Q
N
R
E
D
M
L
Rat
Rattus norvegicus
NP_001099639
874
102795
Y480
V
L
E
I
K
E
W
Y
Q
N
R
E
D
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508368
860
101476
Y465
V
V
E
V
K
E
W
Y
K
N
R
E
D
M
L
Chicken
Gallus gallus
XP_425101
868
101713
F474
A
V
E
V
K
E
W
F
K
N
R
E
D
M
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683491
721
83926
K371
I
L
Q
Y
R
K
A
K
L
E
K
F
A
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036757
897
105223
Y508
P
K
V
R
Y
E
Y
Y
E
N
R
S
D
L
M
Honey Bee
Apis mellifera
XP_396764
568
66652
E218
W
E
H
L
L
P
G
E
P
W
T
T
H
A
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795345
497
57872
D147
V
S
D
Y
V
T
F
D
P
L
D
P
P
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
89.1
81.4
N.A.
82.7
83.9
N.A.
68.6
56.1
N.A.
36.9
N.A.
29.2
24.1
N.A.
31
Protein Similarity:
100
N.A.
91.3
88.5
N.A.
90.1
90.9
N.A.
83.7
70.5
N.A.
53.8
N.A.
49.5
38.4
N.A.
41.4
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
73.3
66.6
N.A.
13.3
N.A.
33.3
0
N.A.
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
93.3
N.A.
40
N.A.
60
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
10
0
73
0
10
% D
% Glu:
0
10
64
0
0
73
0
10
10
10
0
64
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
28
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
64
10
0
10
19
0
10
0
0
0
0
% K
% Leu:
0
55
0
10
10
0
0
0
10
10
0
0
0
10
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
10
0
0
19
0
0
10
10
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
46
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
73
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
10
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% T
% Val:
37
19
10
19
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
10
0
0
0
0
0
64
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
19
10
0
10
64
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _