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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC135
All Species:
18.48
Human Site:
S580
Identified Species:
40.67
UniProt:
Q8IY82
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY82
NP_115645.4
874
103497
S580
L
T
L
S
S
A
E
S
N
P
R
P
I
V
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100628
830
97575
S580
L
A
L
S
S
A
E
S
N
P
R
P
I
V
K
Dog
Lupus familis
XP_544386
903
106348
S609
L
A
L
N
S
A
E
S
N
P
R
P
V
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6V3W6
876
103192
S582
L
S
Q
S
S
V
E
S
N
P
R
P
M
V
K
Rat
Rattus norvegicus
NP_001099639
874
102795
S580
L
T
Q
N
S
A
D
S
N
P
R
P
V
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508368
860
101476
E565
L
G
G
I
V
T
T
E
S
N
A
R
P
V
M
Chicken
Gallus gallus
XP_425101
868
101713
T574
V
T
L
A
G
V
G
T
D
V
N
S
R
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683491
721
83926
Q471
L
A
R
R
I
E
K
Q
S
E
M
T
E
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036757
897
105223
L608
K
K
V
T
E
K
F
L
K
A
S
A
N
D
V
Honey Bee
Apis mellifera
XP_396764
568
66652
R318
D
N
L
I
E
S
R
R
N
M
S
F
D
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795345
497
57872
L247
D
L
R
S
K
F
I
L
E
M
E
A
R
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
89.1
81.4
N.A.
82.7
83.9
N.A.
68.6
56.1
N.A.
36.9
N.A.
29.2
24.1
N.A.
31
Protein Similarity:
100
N.A.
91.3
88.5
N.A.
90.1
90.9
N.A.
83.7
70.5
N.A.
53.8
N.A.
49.5
38.4
N.A.
41.4
P-Site Identity:
100
N.A.
93.3
80
N.A.
73.3
73.3
N.A.
13.3
13.3
N.A.
6.6
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
20
40
N.A.
20
N.A.
13.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
0
10
0
37
0
0
0
10
10
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% D
% Glu:
0
0
0
0
19
10
37
10
10
10
10
0
10
0
10
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
10
% F
% Gly:
0
10
10
0
10
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
10
0
10
0
0
0
0
0
19
0
10
% I
% Lys:
10
10
0
0
10
10
10
0
10
0
0
0
0
10
46
% K
% Leu:
64
10
46
0
0
0
0
19
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
19
10
0
10
0
10
% M
% Asn:
0
10
0
19
0
0
0
0
55
10
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
46
0
46
10
10
0
% P
% Gln:
0
0
19
0
0
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
0
19
10
0
0
10
10
0
0
46
10
19
0
0
% R
% Ser:
0
10
0
37
46
10
0
46
19
0
19
10
0
0
0
% S
% Thr:
0
28
0
10
0
10
10
10
0
0
0
10
0
10
0
% T
% Val:
10
0
10
0
10
19
0
0
0
10
0
0
19
55
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _