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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC135
All Species:
24.55
Human Site:
S170
Identified Species:
54
UniProt:
Q8IY82
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY82
NP_115645.4
874
103497
S170
P
D
P
L
K
P
P
S
H
L
Y
S
S
T
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100628
830
97575
S170
P
D
P
L
K
P
P
S
H
L
Y
S
S
T
T
Dog
Lupus familis
XP_544386
903
106348
S199
P
D
P
L
K
P
P
S
H
L
Y
S
S
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6V3W6
876
103192
T171
V
D
P
L
K
P
P
T
H
L
Y
S
S
T
T
Rat
Rattus norvegicus
NP_001099639
874
102795
T171
V
D
P
L
K
P
P
T
H
L
Y
S
S
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508368
860
101476
S155
P
S
P
L
K
P
P
S
Y
L
Y
S
P
T
S
Chicken
Gallus gallus
XP_425101
868
101713
S164
K
C
P
L
T
P
P
S
S
L
Y
S
P
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683491
721
83926
Q108
S
S
P
T
R
V
L
Q
T
Q
R
G
T
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036757
897
105223
N184
Q
D
P
I
N
L
P
N
R
L
I
S
P
E
T
Honey Bee
Apis mellifera
XP_396764
568
66652
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795345
497
57872
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
89.1
81.4
N.A.
82.7
83.9
N.A.
68.6
56.1
N.A.
36.9
N.A.
29.2
24.1
N.A.
31
Protein Similarity:
100
N.A.
91.3
88.5
N.A.
90.1
90.9
N.A.
83.7
70.5
N.A.
53.8
N.A.
49.5
38.4
N.A.
41.4
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
73.3
66.6
N.A.
6.6
N.A.
40
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
66.6
N.A.
20
N.A.
53.3
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
10
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
64
0
10
10
0
0
73
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
37
0
82
0
0
64
73
0
0
0
0
0
28
0
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% R
% Ser:
10
19
0
0
0
0
0
46
10
0
0
73
46
0
10
% S
% Thr:
0
0
0
10
10
0
0
19
10
0
0
0
10
64
64
% T
% Val:
19
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
64
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _