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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMD2
All Species:
15.45
Human Site:
Y259
Identified Species:
42.5
UniProt:
Q8IY49
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY49
NP_001094070.1
270
31264
Y259
Y
A
I
W
R
Y
L
Y
L
P
S
T
L
Q
T
Chimpanzee
Pan troglodytes
XP_527649
279
31981
Y268
Y
A
I
W
R
Y
L
Y
L
P
S
T
L
Q
T
Rhesus Macaque
Macaca mulatta
XP_001088388
122
14393
Y112
M
F
D
R
M
V
I
Y
F
F
I
A
A
S
Y
Dog
Lupus familis
XP_851666
253
29606
L243
A
I
W
R
Y
L
Y
L
P
S
T
V
Q
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R189
247
28891
Y236
Y
A
I
W
R
Y
L
Y
L
P
S
T
L
Q
T
Rat
Rattus norvegicus
Q719N3
238
27630
Y228
Y
A
I
W
K
Y
L
Y
R
S
P
T
D
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521664
248
28545
Y238
Y
A
I
W
K
Y
L
Y
L
N
P
S
N
I
I
Chicken
Gallus gallus
XP_414787
246
28635
R236
A
I
W
R
Y
L
Y
R
P
G
A
L
E
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572382
313
35229
I300
A
G
C
H
Y
Y
A
I
L
V
N
L
Y
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.1
88.8
N.A.
87.4
61.8
N.A.
61.1
76.3
N.A.
N.A.
N.A.
27.1
N.A.
N.A.
N.A.
Protein Similarity:
100
93.5
45.1
90
N.A.
89.2
71.4
N.A.
72.2
82.5
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
100
53.3
N.A.
53.3
0
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
6.6
N.A.
100
60
N.A.
66.6
6.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
56
0
0
0
0
12
0
0
0
12
12
12
23
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
12
12
0
0
0
12
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
56
0
0
0
12
12
0
0
12
0
0
12
23
% I
% Lys:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
23
% K
% Leu:
0
0
0
0
0
23
56
12
56
0
0
23
34
0
0
% L
% Met:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
12
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
23
34
23
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
34
0
% Q
% Arg:
0
0
0
34
34
0
0
12
12
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
23
34
12
0
12
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
12
45
0
0
34
% T
% Val:
0
0
0
0
0
12
0
0
0
12
0
12
0
0
0
% V
% Trp:
0
0
23
56
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
56
0
0
0
34
67
23
67
0
0
0
0
12
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _