Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMN1 All Species: 17.58
Human Site: S82 Identified Species: 29.74
UniProt: Q8IY45 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY45 NP_001106873.1 258 28408 S82 D A A L L H L S N C R K L K K
Chimpanzee Pan troglodytes XP_520725 429 47022 S253 D A A L L H L S N C R K L K K
Rhesus Macaque Macaca mulatta XP_001084101 402 44332 S226 D A A L L H L S N C R K L K K
Dog Lupus familis XP_852561 258 28481 C82 D T A L L H L C N C R K L K K
Cat Felis silvestris
Mouse Mus musculus Q9CZV8 436 48378 K162 S I T N M S L K A L S E G C P
Rat Rattus norvegicus Q5U201 258 28448 C82 D V A L Q H L C K C R K L K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510661 209 22688 N52 R P S G G G R N I P R Y I S D
Chicken Gallus gallus XP_416368 266 29320 Y90 D N A L L Q L Y N C K Q L K K
Frog Xenopus laevis NP_001087065 436 48338 K162 S I T N L S L K A I S E G C P
Zebra Danio Brachydanio rerio Q0P4D1 249 27093 L80 A L K Q I N S L H L R T I L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795493 219 24296 L62 L P C F L S Q L D N L P I N V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001142195 368 39809 Y176 F S D T A L I Y L T C R C K N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49286 360 39891 S84 N M N S L V L S L A P K F V K
Baker's Yeast Sacchar. cerevisiae P38285 549 62668 T255 N R L W L N V T R P F L F K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.9 63.6 91.4 N.A. 21.7 79.8 N.A. 23.6 66.5 22.4 46.1 N.A. N.A. N.A. N.A. 22.4
Protein Similarity: 100 60.1 64.1 96.1 N.A. 36.2 89.1 N.A. 36.8 78.9 36 64.7 N.A. N.A. N.A. N.A. 42.6
P-Site Identity: 100 100 100 86.6 N.A. 6.6 66.6 N.A. 6.6 66.6 13.3 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 20 66.6 N.A. 26.6 80 20 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 23.6 N.A. 21.9 20 N.A.
Protein Similarity: N.A. 41 N.A. 39.7 30.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 33.3 13.3 N.A.
P-Site Similarity: N.A. 26.6 N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 43 0 8 0 0 0 15 8 0 0 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 15 0 43 8 0 8 15 0 % C
% Asp: 43 0 8 0 0 0 0 0 8 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % E
% Phe: 8 0 0 8 0 0 0 0 0 0 8 0 15 0 0 % F
% Gly: 0 0 0 8 8 8 0 0 0 0 0 0 15 0 0 % G
% His: 0 0 0 0 0 36 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 8 0 8 0 8 8 0 0 22 0 0 % I
% Lys: 0 0 8 0 0 0 0 15 8 0 8 43 0 58 43 % K
% Leu: 8 8 8 43 65 8 65 15 15 15 8 8 43 8 8 % L
% Met: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 8 8 15 0 15 0 8 36 8 0 0 0 8 8 % N
% Pro: 0 15 0 0 0 0 0 0 0 15 8 8 0 0 15 % P
% Gln: 0 0 0 8 8 8 8 0 0 0 0 8 0 0 0 % Q
% Arg: 8 8 0 0 0 0 8 0 8 0 50 8 0 0 0 % R
% Ser: 15 8 8 8 0 22 8 29 0 0 15 0 0 8 8 % S
% Thr: 0 8 15 8 0 0 0 8 0 8 0 8 0 0 0 % T
% Val: 0 8 0 0 0 8 8 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 15 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _