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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMN1 All Species: 18.18
Human Site: S8 Identified Species: 30.77
UniProt: Q8IY45 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY45 NP_001106873.1 258 28408 S8 M P R P R R V S Q L L D L C L
Chimpanzee Pan troglodytes XP_520725 429 47022 S179 M P R P R R V S Q L L D L C L
Rhesus Macaque Macaca mulatta XP_001084101 402 44332 S152 M P R P R R V S Q L L D L C L
Dog Lupus familis XP_852561 258 28481 S8 M P S S R R V S Q L L D L C L
Cat Felis silvestris
Mouse Mus musculus Q9CZV8 436 48378 P29 A V I N K K L P K E L L L R I
Rat Rattus norvegicus Q5U201 258 28448 S8 M P S S R V V S Q L L E L C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510661 209 22688
Chicken Gallus gallus XP_416368 266 29320 R16 D G A S G E A R L L L D L C V
Frog Xenopus laevis NP_001087065 436 48338 P29 A L I N K K L P K E L L L R I
Zebra Danio Brachydanio rerio Q0P4D1 249 27093 M8 M A T I D S L M S L C A F S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795493 219 24296
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001142195 368 39809 T38 G G P A P T L T G W K D L P M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49286 360 39891 L13 A T R K E L N L C F E N M K M
Baker's Yeast Sacchar. cerevisiae P38285 549 62668 E174 F E I P E I V E N I I K M I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.9 63.6 91.4 N.A. 21.7 79.8 N.A. 23.6 66.5 22.4 46.1 N.A. N.A. N.A. N.A. 22.4
Protein Similarity: 100 60.1 64.1 96.1 N.A. 36.2 89.1 N.A. 36.8 78.9 36 64.7 N.A. N.A. N.A. N.A. 42.6
P-Site Identity: 100 100 100 86.6 N.A. 13.3 73.3 N.A. 0 33.3 13.3 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 46.6 80 N.A. 0 40 46.6 26.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. 23.6 N.A. 21.9 20 N.A.
Protein Similarity: N.A. 41 N.A. 39.7 30.9 N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. 33.3 N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 8 8 0 0 8 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 8 0 0 43 0 % C
% Asp: 8 0 0 0 8 0 0 0 0 0 0 43 0 0 0 % D
% Glu: 0 8 0 0 15 8 0 8 0 15 8 8 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 8 15 0 0 8 0 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 22 8 0 8 0 0 0 8 8 0 0 8 15 % I
% Lys: 0 0 0 8 15 15 0 0 15 0 8 8 0 8 0 % K
% Leu: 0 8 0 0 0 8 29 8 8 50 58 15 65 0 36 % L
% Met: 43 0 0 0 0 0 0 8 0 0 0 0 15 0 15 % M
% Asn: 0 0 0 15 0 0 8 0 8 0 0 8 0 0 0 % N
% Pro: 0 36 8 29 8 0 0 15 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 % Q
% Arg: 0 0 29 0 36 29 0 8 0 0 0 0 0 15 0 % R
% Ser: 0 0 15 22 0 8 0 36 8 0 0 0 0 8 0 % S
% Thr: 0 8 8 0 0 8 0 8 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 8 43 0 0 0 0 0 0 0 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _