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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMN1 All Species: 21.21
Human Site: S70 Identified Species: 35.9
UniProt: Q8IY45 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY45 NP_001106873.1 258 28408 S70 V Q T L D L R S C D I S D A A
Chimpanzee Pan troglodytes XP_520725 429 47022 S241 V Q T L D L R S C D I S D A A
Rhesus Macaque Macaca mulatta XP_001084101 402 44332 S214 V Q T L D L R S C D I S D A A
Dog Lupus familis XP_852561 258 28481 S70 V Q T L D L R S C D I S D T A
Cat Felis silvestris
Mouse Mus musculus Q9CZV8 436 48378 L150 S K L R H L D L A S C T S I T
Rat Rattus norvegicus Q5U201 258 28448 S70 V Q R L D L R S C N I S D V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510661 209 22688 V40 C A A Q D G A V L F R G R P S
Chicken Gallus gallus XP_416368 266 29320 E78 V E S L D L R E C D I S D N A
Frog Xenopus laevis NP_001087065 436 48338 L150 S K L R Q L D L A S C T S I T
Zebra Danio Brachydanio rerio Q0P4D1 249 27093 K68 T L D L Q N C K I S D S A L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795493 219 24296 F50 T G R W L Y R F E V L H L P C
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001142195 368 39809 S164 R L T R L N I S G C S S F S D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49286 360 39891 S72 G L T R L S L S W C K K N M N
Baker's Yeast Sacchar. cerevisiae P38285 549 62668 S243 K K Q G A L F S C M M V N R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.9 63.6 91.4 N.A. 21.7 79.8 N.A. 23.6 66.5 22.4 46.1 N.A. N.A. N.A. N.A. 22.4
Protein Similarity: 100 60.1 64.1 96.1 N.A. 36.2 89.1 N.A. 36.8 78.9 36 64.7 N.A. N.A. N.A. N.A. 42.6
P-Site Identity: 100 100 100 93.3 N.A. 6.6 80 N.A. 6.6 73.3 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 20 86.6 N.A. 13.3 86.6 20 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. 23.6 N.A. 21.9 20 N.A.
Protein Similarity: N.A. 41 N.A. 39.7 30.9 N.A.
P-Site Identity: N.A. 20 N.A. 13.3 20 N.A.
P-Site Similarity: N.A. 26.6 N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 0 8 0 15 0 0 0 8 22 43 % A
% Cys: 8 0 0 0 0 0 8 0 50 15 15 0 0 0 8 % C
% Asp: 0 0 8 0 50 0 15 0 0 36 8 0 43 0 8 % D
% Glu: 0 8 0 0 0 0 0 8 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 8 0 8 0 0 8 0 0 % F
% Gly: 8 8 0 8 0 8 0 0 8 0 0 8 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 0 43 0 0 15 0 % I
% Lys: 8 22 0 0 0 0 0 8 0 0 8 8 0 0 8 % K
% Leu: 0 22 15 50 22 65 8 15 8 0 8 0 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % M
% Asn: 0 0 0 0 0 15 0 0 0 8 0 0 15 8 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % P
% Gln: 0 36 8 8 15 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 15 29 0 0 50 0 0 0 8 0 8 8 0 % R
% Ser: 15 0 8 0 0 8 0 58 0 22 8 58 15 8 8 % S
% Thr: 15 0 43 0 0 0 0 0 0 0 0 15 0 8 15 % T
% Val: 43 0 0 0 0 0 0 8 0 8 0 8 0 8 0 % V
% Trp: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _