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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX37
All Species:
22.42
Human Site:
Y452
Identified Species:
44.85
UniProt:
Q8IY37
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY37
NP_116045.2
1157
129545
Y452
K
R
T
P
L
E
D
Y
S
G
E
C
F
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103101
1146
127695
K448
Y
S
G
E
C
F
R
K
I
C
K
I
H
R
M
Dog
Lupus familis
XP_534640
1149
128641
Y446
K
R
T
P
L
E
D
Y
S
G
E
C
F
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
I395
E
Y
L
L
E
D
I
I
E
K
I
R
Y
V
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508258
1135
128020
Y436
K
R
T
P
L
D
D
Y
S
G
E
C
F
R
K
Chicken
Gallus gallus
XP_415104
1141
127222
Y442
K
K
T
P
L
D
D
Y
S
G
E
C
F
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076473
1152
129559
Y452
K
R
T
P
M
D
D
Y
T
G
E
T
F
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46072
1192
134102
V459
K
R
T
P
D
D
Y
V
A
E
A
Y
R
K
T
Honey Bee
Apis mellifera
XP_001121639
1118
128185
F440
V
Q
K
L
R
Q
A
F
S
T
K
N
K
K
K
Nematode Worm
Caenorhab. elegans
P34305
1148
129944
I435
K
R
T
P
D
D
Y
I
A
S
A
F
R
K
T
Sea Urchin
Strong. purpuratus
XP_786550
1324
147742
Y625
K
R
T
P
V
E
D
Y
I
T
E
V
H
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04217
1267
144936
T603
R
R
T
A
F
N
Y
T
D
E
A
F
R
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
86.5
N.A.
23.1
N.A.
N.A.
73.1
72.1
N.A.
66.2
N.A.
45.5
48.1
41.4
49.4
Protein Similarity:
100
N.A.
96.1
92
N.A.
42.2
N.A.
N.A.
84
83.4
N.A.
78.8
N.A.
63.3
66.6
57.3
63.9
P-Site Identity:
100
N.A.
6.6
100
N.A.
0
N.A.
N.A.
93.3
86.6
N.A.
73.3
N.A.
26.6
13.3
26.6
66.6
P-Site Similarity:
100
N.A.
13.3
100
N.A.
20
N.A.
N.A.
100
100
N.A.
93.3
N.A.
46.6
46.6
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
0
17
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
9
0
34
0
0
0
% C
% Asp:
0
0
0
0
17
50
50
0
9
0
0
0
0
0
0
% D
% Glu:
9
0
0
9
9
25
0
0
9
17
50
0
0
0
0
% E
% Phe:
0
0
0
0
9
9
0
9
0
0
0
17
42
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
42
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% H
% Ile:
0
0
0
0
0
0
9
17
17
0
9
9
0
0
0
% I
% Lys:
67
9
9
0
0
0
0
9
0
9
17
0
9
34
59
% K
% Leu:
0
0
9
17
34
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
67
0
0
9
0
9
0
0
0
0
9
25
59
0
% R
% Ser:
0
9
0
0
0
0
0
0
42
9
0
0
0
0
0
% S
% Thr:
0
0
75
0
0
0
0
9
9
17
0
9
0
0
25
% T
% Val:
9
0
0
0
9
0
0
9
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
25
50
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _