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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX37
All Species:
14.55
Human Site:
Y126
Identified Species:
29.09
UniProt:
Q8IY37
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY37
NP_116045.2
1157
129545
Y126
L
G
T
G
N
R
M
Y
H
T
K
E
K
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103101
1146
127695
Y126
L
G
T
G
D
R
M
Y
H
T
K
Q
K
P
D
Dog
Lupus familis
XP_534640
1149
128641
Y126
L
G
T
G
D
R
M
Y
H
T
R
E
K
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
S94
Q
I
V
Q
L
L
N
S
V
Q
A
K
T
D
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508258
1135
128020
G125
I
E
E
V
G
A
L
G
P
D
K
I
S
S
I
Chicken
Gallus gallus
XP_415104
1141
127222
Y127
L
G
I
G
G
R
M
Y
Q
P
K
R
V
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076473
1152
129559
Y125
L
G
T
G
G
K
L
Y
H
I
K
E
S
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46072
1192
134102
R123
V
Q
T
V
G
L
K
R
L
P
T
L
D
E
Y
Honey Bee
Apis mellifera
XP_001121639
1118
128185
K126
Q
M
P
I
N
A
I
K
V
S
K
K
K
R
L
Nematode Worm
Caenorhab. elegans
P34305
1148
129944
F121
F
P
E
K
L
K
V
F
S
G
K
T
K
T
E
Sea Urchin
Strong. purpuratus
XP_786550
1324
147742
R138
I
G
Q
K
I
N
K
R
K
L
D
N
T
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04217
1267
144936
K140
L
G
E
G
R
Q
T
K
K
E
E
F
K
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
86.5
N.A.
23.1
N.A.
N.A.
73.1
72.1
N.A.
66.2
N.A.
45.5
48.1
41.4
49.4
Protein Similarity:
100
N.A.
96.1
92
N.A.
42.2
N.A.
N.A.
84
83.4
N.A.
78.8
N.A.
63.3
66.6
57.3
63.9
P-Site Identity:
100
N.A.
80
80
N.A.
0
N.A.
N.A.
6.6
46.6
N.A.
53.3
N.A.
6.6
20
13.3
6.6
P-Site Similarity:
100
N.A.
93.3
100
N.A.
6.6
N.A.
N.A.
26.6
46.6
N.A.
73.3
N.A.
13.3
40
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
9
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
0
0
0
0
9
9
0
9
9
25
% D
% Glu:
0
9
25
0
0
0
0
0
0
9
9
25
0
17
9
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% F
% Gly:
0
59
0
50
34
0
0
9
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% H
% Ile:
17
9
9
9
9
0
9
0
0
9
0
9
0
0
9
% I
% Lys:
0
0
0
17
0
17
17
17
17
0
59
17
50
0
9
% K
% Leu:
50
0
0
0
17
17
17
0
9
9
0
9
0
9
9
% L
% Met:
0
9
0
0
0
0
34
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
9
9
0
0
0
0
9
0
0
9
% N
% Pro:
0
9
9
0
0
0
0
0
9
17
0
0
0
9
9
% P
% Gln:
17
9
9
9
0
9
0
0
9
9
0
9
0
0
9
% Q
% Arg:
0
0
0
0
9
34
0
17
0
0
9
9
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
9
9
9
0
0
17
17
0
% S
% Thr:
0
0
42
0
0
0
9
0
0
25
9
9
17
9
0
% T
% Val:
9
0
9
17
0
0
9
0
17
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _