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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX37
All Species:
21.82
Human Site:
Y1025
Identified Species:
43.64
UniProt:
Q8IY37
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY37
NP_116045.2
1157
129545
Y1025
L
E
E
P
A
P
T
Y
C
P
E
R
G
R
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103101
1146
127695
Y1014
L
E
E
P
A
P
T
Y
C
P
E
R
G
R
V
Dog
Lupus familis
XP_534640
1149
128641
Y1019
L
E
E
P
P
P
V
Y
C
P
E
K
G
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
Y893
R
T
S
S
I
Y
L
Y
D
C
T
E
V
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508258
1135
128020
Y1004
L
E
D
P
P
P
A
Y
C
H
E
S
G
R
V
Chicken
Gallus gallus
XP_415104
1141
127222
Y1010
L
E
N
P
P
P
S
Y
C
P
E
T
G
R
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076473
1152
129559
F1017
E
E
S
P
A
P
R
F
C
P
L
I
G
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46072
1192
134102
F1055
R
E
D
P
A
P
R
F
D
K
T
S
G
K
I
Honey Bee
Apis mellifera
XP_001121639
1118
128185
Y989
L
T
D
P
P
P
R
Y
D
P
E
T
G
K
I
Nematode Worm
Caenorhab. elegans
P34305
1148
129944
I1003
Q
D
K
N
Q
E
P
I
Y
D
P
V
K
D
M
Sea Urchin
Strong. purpuratus
XP_786550
1324
147742
Y1191
L
E
E
P
S
P
S
Y
H
S
S
S
G
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04217
1267
144936
E1146
S
I
L
N
N
L
G
E
M
P
P
K
Y
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
86.5
N.A.
23.1
N.A.
N.A.
73.1
72.1
N.A.
66.2
N.A.
45.5
48.1
41.4
49.4
Protein Similarity:
100
N.A.
96.1
92
N.A.
42.2
N.A.
N.A.
84
83.4
N.A.
78.8
N.A.
63.3
66.6
57.3
63.9
P-Site Identity:
100
N.A.
100
80
N.A.
6.6
N.A.
N.A.
66.6
66.6
N.A.
60
N.A.
33.3
46.6
0
53.3
P-Site Similarity:
100
N.A.
100
86.6
N.A.
6.6
N.A.
N.A.
73.3
80
N.A.
66.6
N.A.
60
66.6
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
50
9
0
0
0
0
0
% C
% Asp:
0
9
25
0
0
0
0
0
25
9
0
0
0
9
0
% D
% Glu:
9
67
34
0
0
9
0
9
0
0
50
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
75
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
9
0
0
0
9
0
0
25
% I
% Lys:
0
0
9
0
0
0
0
0
0
9
0
17
9
17
0
% K
% Leu:
59
0
9
0
0
9
9
0
0
0
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% M
% Asn:
0
0
9
17
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
75
34
75
9
0
0
59
17
0
0
0
9
% P
% Gln:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
0
0
0
0
25
0
0
0
0
17
0
50
0
% R
% Ser:
9
0
17
9
9
0
17
0
0
9
9
25
0
9
0
% S
% Thr:
0
17
0
0
0
0
17
0
0
0
17
17
0
9
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
9
9
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
67
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _