KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX37
All Species:
37.27
Human Site:
S653
Identified Species:
74.55
UniProt:
Q8IY37
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY37
NP_116045.2
1157
129545
S653
Y
D
R
V
T
G
V
S
S
F
R
V
T
W
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103101
1146
127695
S642
Y
D
R
V
T
G
V
S
S
F
R
V
T
W
V
Dog
Lupus familis
XP_534640
1149
128641
S647
Y
D
R
V
T
G
V
S
S
F
R
V
T
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
D561
D
D
V
V
Y
V
I
D
G
G
K
I
K
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508258
1135
128020
S632
Y
D
K
V
T
G
V
S
S
F
R
V
S
W
T
Chicken
Gallus gallus
XP_415104
1141
127222
S638
Y
D
K
I
T
G
V
S
S
F
R
V
T
W
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076473
1152
129559
S645
Y
D
R
V
T
G
V
S
S
F
K
V
T
W
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46072
1192
134102
S682
Y
D
K
L
T
G
V
S
A
F
V
V
T
Y
T
Honey Bee
Apis mellifera
XP_001121639
1118
128185
S624
Y
D
K
V
T
G
V
S
T
Y
K
V
C
Y
T
Nematode Worm
Caenorhab. elegans
P34305
1148
129944
S640
Y
D
S
I
T
G
V
S
R
F
A
V
C
R
I
Sea Urchin
Strong. purpuratus
XP_786550
1324
147742
S820
Y
D
K
V
T
G
V
S
S
F
K
V
D
W
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04217
1267
144936
Q794
Y
N
E
S
N
G
V
Q
S
F
E
V
G
W
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
86.5
N.A.
23.1
N.A.
N.A.
73.1
72.1
N.A.
66.2
N.A.
45.5
48.1
41.4
49.4
Protein Similarity:
100
N.A.
96.1
92
N.A.
42.2
N.A.
N.A.
84
83.4
N.A.
78.8
N.A.
63.3
66.6
57.3
63.9
P-Site Identity:
100
N.A.
100
100
N.A.
13.3
N.A.
N.A.
80
80
N.A.
86.6
N.A.
60
53.3
53.3
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
33.3
N.A.
N.A.
93.3
100
N.A.
100
N.A.
86.6
86.6
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% C
% Asp:
9
92
0
0
0
0
0
9
0
0
0
0
9
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
92
0
0
9
9
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
9
0
0
0
0
9
0
0
25
% I
% Lys:
0
0
42
0
0
0
0
0
0
0
34
0
9
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
34
0
0
0
0
0
9
0
42
0
0
9
0
% R
% Ser:
0
0
9
9
0
0
0
84
67
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
84
0
0
0
9
0
0
0
50
0
42
% T
% Val:
0
0
9
67
0
9
92
0
0
0
9
92
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% W
% Tyr:
92
0
0
0
9
0
0
0
0
9
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _