KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX37
All Species:
31.82
Human Site:
S378
Identified Species:
63.64
UniProt:
Q8IY37
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY37
NP_116045.2
1157
129545
S378
I
D
E
A
H
E
R
S
V
Y
T
D
I
L
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103101
1146
127695
L374
S
T
P
T
V
L
L
L
G
V
L
R
R
E
A
Dog
Lupus familis
XP_534640
1149
128641
S372
I
D
E
A
H
E
R
S
V
Y
T
D
I
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
H323
S
R
L
S
S
V
S
H
I
V
L
D
E
I
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508258
1135
128020
S362
I
D
E
A
H
E
R
S
V
Y
T
D
I
L
I
Chicken
Gallus gallus
XP_415104
1141
127222
S368
I
D
E
A
H
E
R
S
M
Y
T
D
I
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076473
1152
129559
S378
I
D
E
A
H
E
R
S
V
Y
T
D
I
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46072
1192
134102
S385
L
D
E
A
H
E
R
S
V
Y
T
D
I
L
V
Honey Bee
Apis mellifera
XP_001121639
1118
128185
F364
A
T
L
R
V
E
E
F
I
E
N
N
K
L
F
Nematode Worm
Caenorhab. elegans
P34305
1148
129944
S361
I
D
E
A
H
E
R
S
M
Y
S
D
V
L
I
Sea Urchin
Strong. purpuratus
XP_786550
1324
147742
S551
I
D
E
A
H
E
R
S
V
Y
T
D
I
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04217
1267
144936
N522
I
D
E
A
H
E
R
N
I
N
T
D
I
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
86.5
N.A.
23.1
N.A.
N.A.
73.1
72.1
N.A.
66.2
N.A.
45.5
48.1
41.4
49.4
Protein Similarity:
100
N.A.
96.1
92
N.A.
42.2
N.A.
N.A.
84
83.4
N.A.
78.8
N.A.
63.3
66.6
57.3
63.9
P-Site Identity:
100
N.A.
0
100
N.A.
6.6
N.A.
N.A.
100
93.3
N.A.
100
N.A.
86.6
13.3
80
100
P-Site Similarity:
100
N.A.
0
100
N.A.
26.6
N.A.
N.A.
100
100
N.A.
100
N.A.
100
26.6
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
75
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
0
0
0
0
0
0
0
0
0
84
0
0
0
% D
% Glu:
0
0
75
0
0
84
9
0
0
9
0
0
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
75
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
67
0
0
0
0
0
0
0
25
0
0
0
67
9
67
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
0
17
0
0
9
9
9
0
0
17
0
0
84
0
% L
% Met:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
9
9
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
9
0
0
75
0
0
0
0
9
9
0
0
% R
% Ser:
17
0
0
9
9
0
9
67
0
0
9
0
0
0
0
% S
% Thr:
0
17
0
9
0
0
0
0
0
0
67
0
0
0
0
% T
% Val:
0
0
0
0
17
9
0
0
50
17
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _