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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX37
All Species:
4.55
Human Site:
S171
Identified Species:
9.09
UniProt:
Q8IY37
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY37
NP_116045.2
1157
129545
S171
E
E
E
E
E
S
E
S
E
L
E
E
E
S
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103101
1146
127695
L170
E
E
S
Q
E
S
E
L
E
G
E
S
E
L
D
Dog
Lupus familis
XP_534640
1149
128641
P171
E
P
S
M
E
S
E
P
E
E
A
P
A
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
K138
K
K
L
D
N
Q
E
K
K
L
L
N
Q
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508258
1135
128020
Q169
G
E
Q
T
A
S
E
Q
T
V
I
E
E
E
K
Chicken
Gallus gallus
XP_415104
1141
127222
E172
G
E
S
S
G
S
E
E
E
K
K
E
E
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076473
1152
129559
S172
N
E
S
E
M
S
E
S
S
E
D
D
D
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46072
1192
134102
I181
K
R
K
N
P
N
V
I
S
V
E
E
D
D
E
Honey Bee
Apis mellifera
XP_001121639
1118
128185
D170
S
D
T
K
N
N
E
D
E
Q
E
E
N
Q
L
Nematode Worm
Caenorhab. elegans
P34305
1148
129944
V165
I
E
D
A
G
N
T
V
E
V
K
I
E
P
I
Sea Urchin
Strong. purpuratus
XP_786550
1324
147742
S244
K
A
R
T
K
S
E
S
D
N
V
V
K
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04217
1267
144936
D274
D
F
D
T
T
S
E
D
D
D
E
E
E
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
86.5
N.A.
23.1
N.A.
N.A.
73.1
72.1
N.A.
66.2
N.A.
45.5
48.1
41.4
49.4
Protein Similarity:
100
N.A.
96.1
92
N.A.
42.2
N.A.
N.A.
84
83.4
N.A.
78.8
N.A.
63.3
66.6
57.3
63.9
P-Site Identity:
100
N.A.
53.3
40
N.A.
13.3
N.A.
N.A.
33.3
40
N.A.
33.3
N.A.
20
26.6
20
20
P-Site Similarity:
100
N.A.
66.6
46.6
N.A.
53.3
N.A.
N.A.
53.3
53.3
N.A.
53.3
N.A.
53.3
46.6
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
0
0
0
0
9
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
17
9
0
0
0
17
17
9
9
9
17
34
9
% D
% Glu:
25
50
9
17
25
0
84
9
50
17
42
50
50
17
25
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
0
9
9
0
0
9
% I
% Lys:
25
9
9
9
9
0
0
9
9
9
17
0
9
9
17
% K
% Leu:
0
0
9
0
0
0
0
9
0
17
9
0
0
9
9
% L
% Met:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
17
25
0
0
0
9
0
9
9
0
9
% N
% Pro:
0
9
0
0
9
0
0
9
0
0
0
9
0
9
0
% P
% Gln:
0
0
9
9
0
9
0
9
0
9
0
0
9
9
17
% Q
% Arg:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
34
9
0
67
0
25
17
0
0
9
0
9
9
% S
% Thr:
0
0
9
25
9
0
9
0
9
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
9
9
0
25
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _