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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC15A3 All Species: 19.7
Human Site: S366 Identified Species: 36.11
UniProt: Q8IY34 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY34 NP_057666.1 581 63560 S366 V A L R A Q G S S Y T I P E A
Chimpanzee Pan troglodytes XP_508467 527 57583 S312 V S L R A Q G S S Y T I P E A
Rhesus Macaque Macaca mulatta XP_001084703 580 62690 S365 M A L R A Q G S S Y T I P E A
Dog Lupus familis XP_852542 566 61087 A360 T P H T F P A A W L T M F D A
Cat Felis silvestris
Mouse Mus musculus Q8BPX9 578 64032 S363 L L L R S D S S N Y R I P E A
Rat Rattus norvegicus Q924V4 582 64575 S367 L P L R S D S S N Y R I P E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508474 657 71951 A417 T P H T F P A A W L T M F D A
Chicken Gallus gallus XP_415099 492 54115 V307 I P L K D K L V D P V L K R N
Frog Xenopus laevis Q68F72 569 63068 L370 H T L P A A W L T M F D A V L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783351 614 68101 S385 T F P V A W L S L F D V V V V
Poplar Tree Populus trichocarpa XP_002315835 584 64173 S395 I P P A S L S S F D V I S V I
Maize Zea mays NP_001146682 587 64502 T397 I P P A S L S T F D T L S V I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFB8 570 63290 L377 I P S A S L S L F D T L S V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.5 88.6 50.5 N.A. 80.7 80.9 N.A. 35.6 43.8 48.1 N.A. N.A. N.A. N.A. N.A. 39.2
Protein Similarity: 100 89.8 91.3 66.9 N.A. 86.5 86.7 N.A. 50.8 58.6 66.6 N.A. N.A. N.A. N.A. N.A. 54.5
P-Site Identity: 100 93.3 93.3 13.3 N.A. 53.3 53.3 N.A. 13.3 6.6 13.3 N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 33.3 N.A. 73.3 73.3 N.A. 33.3 33.3 20 N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 28 28.4 N.A. 25.8 N.A. N.A.
Protein Similarity: 47.4 47.3 N.A. 46.3 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 33.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 24 39 8 16 16 0 0 0 0 8 0 54 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 16 0 0 8 24 8 8 0 16 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 39 0 % E
% Phe: 0 8 0 0 16 0 0 0 24 8 8 0 16 0 0 % F
% Gly: 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 % G
% His: 8 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 31 0 0 0 0 0 0 0 0 0 0 47 0 0 16 % I
% Lys: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % K
% Leu: 16 8 54 0 0 24 16 16 8 16 0 24 0 0 16 % L
% Met: 8 0 0 0 0 0 0 0 0 8 0 16 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 8 % N
% Pro: 0 54 24 8 0 16 0 0 0 8 0 0 39 0 0 % P
% Gln: 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 39 0 0 0 0 0 0 16 0 0 8 0 % R
% Ser: 0 8 8 0 39 0 39 54 24 0 0 0 24 0 0 % S
% Thr: 24 8 0 16 0 0 0 8 8 0 54 0 0 0 0 % T
% Val: 16 0 0 8 0 0 0 8 0 0 16 8 8 39 8 % V
% Trp: 0 0 0 0 0 8 8 0 16 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _