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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H3 All Species: 9.09
Human Site: Y62 Identified Species: 18.18
UniProt: Q8IXZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXZ2 NP_055932.2 948 101930 Y62 P R P S R R G Y S S H H G P S
Chimpanzee Pan troglodytes XP_519998 1257 135558 Y367 P R P S R R G Y S S H H G P S
Rhesus Macaque Macaca mulatta XP_001097060 1074 115065 Y190 P R P S R R G Y S S H H G P S
Dog Lupus familis XP_539198 1016 109897 F126 P R P S R R G F P L N H G P A
Cat Felis silvestris
Mouse Mus musculus Q8CHP0 950 103206 F62 S R P S R R G F S S H H G P S
Rat Rattus norvegicus NP_001128337 952 103496 F62 S R P N R R G F S S H H G P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518934 951 103158 L49 C A T R D L V L D S L V P L L
Chicken Gallus gallus NP_001026756 956 105809 F66 Q L Q P P R D F Q L R R A H S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689680 929 101372 H52 G Q G Q G R G H A A H Y T Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648230 597 66304
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785788 1142 125989 Q83 S A F H K Q G Q R S Q G P S C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3ED78 470 53750
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.8 82.8 70.8 N.A. 70.6 70.6 N.A. 47.7 42.4 N.A. 36.3 N.A. 22.4 N.A. N.A. 25.6
Protein Similarity: 100 74.4 84.3 77.9 N.A. 79.5 79.3 N.A. 57.2 56.2 N.A. 52 N.A. 37.2 N.A. N.A. 38.7
P-Site Identity: 100 100 100 66.6 N.A. 86.6 80 N.A. 6.6 13.3 N.A. 26.6 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 6.6 20 N.A. 60 N.A. 0 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 21.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 0 0 0 9 9 0 0 9 0 9 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 9 0 9 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 34 0 0 0 0 0 0 0 % F
% Gly: 9 0 9 0 9 0 67 0 0 0 0 9 50 0 0 % G
% His: 0 0 0 9 0 0 0 9 0 0 50 50 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 0 9 0 9 0 17 9 0 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 34 0 50 9 9 0 0 0 9 0 0 0 17 50 0 % P
% Gln: 9 9 9 9 0 9 0 9 9 0 9 0 0 9 0 % Q
% Arg: 0 50 0 9 50 67 0 0 9 0 9 9 0 0 0 % R
% Ser: 25 0 0 42 0 0 0 0 42 59 0 0 0 9 59 % S
% Thr: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 25 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _