KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H3
All Species:
23.64
Human Site:
Y54
Identified Species:
47.27
UniProt:
Q8IXZ2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXZ2
NP_055932.2
948
101930
Y54
G
R
A
F
S
A
R
Y
P
R
P
S
R
R
G
Chimpanzee
Pan troglodytes
XP_519998
1257
135558
Y359
G
R
A
F
S
A
R
Y
P
R
P
S
R
R
G
Rhesus Macaque
Macaca mulatta
XP_001097060
1074
115065
Y182
G
R
A
F
S
A
R
Y
P
R
P
S
R
R
G
Dog
Lupus familis
XP_539198
1016
109897
Y118
S
R
S
F
S
A
C
Y
P
R
P
S
R
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHP0
950
103206
Y54
G
R
T
F
G
A
R
Y
S
R
P
S
R
R
G
Rat
Rattus norvegicus
NP_001128337
952
103496
Y54
G
R
T
F
G
S
R
Y
S
R
P
N
R
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518934
951
103158
R41
G
R
S
P
L
L
Q
R
C
A
T
R
D
L
V
Chicken
Gallus gallus
NP_001026756
956
105809
P58
G
A
F
S
A
R
Y
P
Q
L
Q
P
P
R
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689680
929
101372
S44
H
P
R
R
G
L
R
S
G
Q
G
Q
G
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648230
597
66304
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785788
1142
125989
T75
S
S
S
Q
S
S
K
T
S
A
F
H
K
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3ED78
470
53750
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
82.8
70.8
N.A.
70.6
70.6
N.A.
47.7
42.4
N.A.
36.3
N.A.
22.4
N.A.
N.A.
25.6
Protein Similarity:
100
74.4
84.3
77.9
N.A.
79.5
79.3
N.A.
57.2
56.2
N.A.
52
N.A.
37.2
N.A.
N.A.
38.7
P-Site Identity:
100
100
100
80
N.A.
80
66.6
N.A.
13.3
13.3
N.A.
20
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
26.6
20
N.A.
26.6
N.A.
0
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
0
9
42
0
0
0
17
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
50
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
59
0
0
0
25
0
0
0
9
0
9
0
9
0
67
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
9
17
0
0
0
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
9
34
0
50
9
9
0
0
% P
% Gln:
0
0
0
9
0
0
9
0
9
9
9
9
0
9
0
% Q
% Arg:
0
59
9
9
0
9
50
9
0
50
0
9
50
67
0
% R
% Ser:
17
9
25
9
42
17
0
9
25
0
0
42
0
0
0
% S
% Thr:
0
0
17
0
0
0
0
9
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _