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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H3
All Species:
15.15
Human Site:
S874
Identified Species:
30.3
UniProt:
Q8IXZ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXZ2
NP_055932.2
948
101930
S874
P
S
S
S
K
A
S
S
S
S
S
S
S
S
S
Chimpanzee
Pan troglodytes
XP_519998
1257
135558
S1179
P
A
S
S
K
A
S
S
S
S
S
S
C
S
S
Rhesus Macaque
Macaca mulatta
XP_001097060
1074
115065
S1000
S
L
K
A
S
S
S
S
C
S
S
S
S
S
S
Dog
Lupus familis
XP_539198
1016
109897
S938
P
P
S
S
P
S
P
S
S
P
L
S
P
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHP0
950
103206
A869
T
S
T
L
S
S
K
A
T
A
A
S
S
P
S
Rat
Rattus norvegicus
NP_001128337
952
103496
S878
T
A
A
S
S
P
S
S
S
P
S
T
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518934
951
103158
C857
S
Y
F
L
K
G
I
C
S
N
S
N
C
P
Y
Chicken
Gallus gallus
NP_001026756
956
105809
K875
E
E
D
V
K
F
W
K
E
A
D
T
T
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689680
929
101372
T856
R
S
S
D
A
A
Q
T
Q
S
S
E
S
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648230
597
66304
E526
A
F
T
D
T
A
K
E
S
S
T
A
D
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785788
1142
125989
F1060
E
S
G
S
M
P
S
F
I
A
L
D
S
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3ED78
470
53750
H399
R
R
Y
F
S
S
L
H
N
I
L
S
E
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
82.8
70.8
N.A.
70.6
70.6
N.A.
47.7
42.4
N.A.
36.3
N.A.
22.4
N.A.
N.A.
25.6
Protein Similarity:
100
74.4
84.3
77.9
N.A.
79.5
79.3
N.A.
57.2
56.2
N.A.
52
N.A.
37.2
N.A.
N.A.
38.7
P-Site Identity:
100
86.6
53.3
46.6
N.A.
26.6
46.6
N.A.
20
13.3
N.A.
40
N.A.
20
N.A.
N.A.
33.3
P-Site Similarity:
100
93.3
66.6
53.3
N.A.
66.6
66.6
N.A.
33.3
33.3
N.A.
53.3
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
9
9
34
0
9
0
25
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
9
0
0
0
17
0
0
% C
% Asp:
0
0
9
17
0
0
0
0
0
0
9
9
9
9
0
% D
% Glu:
17
9
0
0
0
0
0
9
9
0
0
9
9
9
9
% E
% Phe:
0
9
9
9
0
9
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
34
0
17
9
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
17
0
0
9
0
0
0
25
0
0
0
17
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
9
0
0
0
% N
% Pro:
25
9
0
0
9
17
9
0
0
17
0
0
9
25
0
% P
% Gln:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
17
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
17
34
34
42
34
34
42
42
50
42
50
50
42
42
67
% S
% Thr:
17
0
17
0
9
0
0
9
9
0
9
17
9
9
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _