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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H3 All Species: 18.79
Human Site: S84 Identified Species: 37.58
UniProt: Q8IXZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXZ2 NP_055932.2 948 101930 S84 V N R P P G P S D P P A D H A
Chimpanzee Pan troglodytes XP_519998 1257 135558 S389 V N R P P G P S D P P A D H A
Rhesus Macaque Macaca mulatta XP_001097060 1074 115065 S212 V N R P P G P S D P P A D P A
Dog Lupus familis XP_539198 1016 109897 S148 V N R P P G S S D P P G D C A
Cat Felis silvestris
Mouse Mus musculus Q8CHP0 950 103206 S84 V N Q P V E S S D P A S D P A
Rat Rattus norvegicus NP_001128337 952 103496 S84 V N Q P L E S S D P A S D H A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518934 951 103158 E71 P D A A E S A E W T L A R C D
Chicken Gallus gallus NP_001026756 956 105809 V88 V N Q P P G P V C D V G C A T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689680 929 101372 R74 A H S S G S W R K T Y S L N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648230 597 66304
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785788 1142 125989 R105 T W K K V K E R R D D P L T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3ED78 470 53750
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.8 82.8 70.8 N.A. 70.6 70.6 N.A. 47.7 42.4 N.A. 36.3 N.A. 22.4 N.A. N.A. 25.6
Protein Similarity: 100 74.4 84.3 77.9 N.A. 79.5 79.3 N.A. 57.2 56.2 N.A. 52 N.A. 37.2 N.A. N.A. 38.7
P-Site Identity: 100 100 93.3 80 N.A. 53.3 60 N.A. 6.6 40 N.A. 0 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 80 N.A. 66.6 73.3 N.A. 13.3 46.6 N.A. 20 N.A. 0 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 21.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 0 0 9 0 0 0 17 34 0 9 50 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 9 17 0 % C
% Asp: 0 9 0 0 0 0 0 0 50 17 9 0 50 0 9 % D
% Glu: 0 0 0 0 9 17 9 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 42 0 0 0 0 0 17 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 25 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 9 0 9 0 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 9 0 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 59 0 0 0 0 0 0 0 0 0 0 0 9 9 % N
% Pro: 9 0 0 59 42 0 34 0 0 50 34 9 0 17 0 % P
% Gln: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 34 0 0 0 0 17 9 0 0 0 9 0 0 % R
% Ser: 0 0 9 9 0 17 25 50 0 0 0 25 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 17 0 0 0 9 17 % T
% Val: 59 0 0 0 17 0 0 9 0 0 9 0 0 0 0 % V
% Trp: 0 9 0 0 0 0 9 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _