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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H3 All Species: 5.15
Human Site: S810 Identified Species: 10.3
UniProt: Q8IXZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXZ2 NP_055932.2 948 101930 S810 H S R R A A T S P A P G P S D
Chimpanzee Pan troglodytes XP_519998 1257 135558 S1115 H S R R A A T S P A P G P S D
Rhesus Macaque Macaca mulatta XP_001097060 1074 115065 A936 K R H S R R A A T S P A P G P
Dog Lupus familis XP_539198 1016 109897 A874 L G R R A A S A P A S E P G S
Cat Felis silvestris
Mouse Mus musculus Q8CHP0 950 103206 P805 H G R R T A A P P I P G P S D
Rat Rattus norvegicus NP_001128337 952 103496 G814 P I P G P S D G T P R S K A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518934 951 103158 C793 K E K K K D Y C M Y Y N R F G
Chicken Gallus gallus NP_001026756 956 105809 G811 K K G I C P R G A C C K L L H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689680 929 101372 Q792 F V R G Y C P Q G D K C K K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648230 597 66304 R462 E I C I D F V R G Y C P L A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785788 1142 125989 G996 K R K T K S E G R K G V K R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3ED78 470 53750 Y335 C D G F L K G Y C S E G D E C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.8 82.8 70.8 N.A. 70.6 70.6 N.A. 47.7 42.4 N.A. 36.3 N.A. 22.4 N.A. N.A. 25.6
Protein Similarity: 100 74.4 84.3 77.9 N.A. 79.5 79.3 N.A. 57.2 56.2 N.A. 52 N.A. 37.2 N.A. N.A. 38.7
P-Site Identity: 100 100 13.3 46.6 N.A. 66.6 0 N.A. 0 0 N.A. 6.6 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 26.6 60 N.A. 66.6 13.3 N.A. 13.3 0 N.A. 6.6 N.A. 6.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 21.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 25 34 17 17 9 25 0 9 0 17 9 % A
% Cys: 9 0 9 0 9 9 0 9 9 9 17 9 0 0 9 % C
% Asp: 0 9 0 0 9 9 9 0 0 9 0 0 9 0 25 % D
% Glu: 9 9 0 0 0 0 9 0 0 0 9 9 0 9 0 % E
% Phe: 9 0 0 9 0 9 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 17 17 17 0 0 9 25 17 0 9 34 0 17 9 % G
% His: 25 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 17 0 17 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 34 9 17 9 17 9 0 0 0 9 9 9 25 9 9 % K
% Leu: 9 0 0 0 9 0 0 0 0 0 0 0 17 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 9 0 9 0 9 9 9 9 34 9 34 9 42 0 9 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 17 42 34 9 9 9 9 9 0 9 0 9 9 9 % R
% Ser: 0 17 0 9 0 17 9 17 0 17 9 9 0 25 17 % S
% Thr: 0 0 0 9 9 0 17 0 17 0 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 9 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 9 9 0 17 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _