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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H3 All Species: 13.33
Human Site: S655 Identified Species: 26.67
UniProt: Q8IXZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXZ2 NP_055932.2 948 101930 S655 A S R A V Q R S L A I I R Q A
Chimpanzee Pan troglodytes XP_519998 1257 135558 S960 A S R A V Q R S L A I I R Q A
Rhesus Macaque Macaca mulatta XP_001097060 1074 115065 S783 A S R A V Q R S L A I I R Q A
Dog Lupus familis XP_539198 1016 109897 L719 S R A V Q R S L A I V R Q A R
Cat Felis silvestris
Mouse Mus musculus Q8CHP0 950 103206 A652 R A I Q R S L A I I R Q A K Q
Rat Rattus norvegicus NP_001128337 952 103496 A653 R A I Q R S L A I I R Q A K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518934 951 103158 R646 G S S I H T F R S P L G G K V
Chicken Gallus gallus NP_001026756 956 105809 S665 C L N R S A T S R Y I A S R A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689680 929 101372 Y630 R W I G G E L Y R V S A N K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648230 597 66304 S318 T Q S S V N R S I L R R I D I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785788 1142 125989 Y823 T A S A H R V Y Q R Q G A M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3ED78 470 53750 F191 G K G V K R P F I P K R L V I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.8 82.8 70.8 N.A. 70.6 70.6 N.A. 47.7 42.4 N.A. 36.3 N.A. 22.4 N.A. N.A. 25.6
Protein Similarity: 100 74.4 84.3 77.9 N.A. 79.5 79.3 N.A. 57.2 56.2 N.A. 52 N.A. 37.2 N.A. N.A. 38.7
P-Site Identity: 100 100 100 0 N.A. 0 0 N.A. 6.6 20 N.A. 0 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 26.6 26.6 N.A. 20 26.6 N.A. 13.3 N.A. 33.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 21.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 25 9 34 0 9 0 17 9 25 0 17 25 9 34 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % F
% Gly: 17 0 9 9 9 0 0 0 0 0 0 17 9 0 0 % G
% His: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 25 9 0 0 0 0 34 25 34 25 9 0 17 % I
% Lys: 0 9 0 0 9 0 0 0 0 0 9 0 0 34 9 % K
% Leu: 0 9 0 0 0 0 25 9 25 9 9 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 9 0 0 9 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 17 0 0 0 0 0 % P
% Gln: 0 9 0 17 9 25 0 0 9 0 9 17 9 25 17 % Q
% Arg: 25 9 25 9 17 25 34 9 17 9 25 25 25 9 9 % R
% Ser: 9 34 25 9 9 17 9 42 9 0 9 0 9 0 0 % S
% Thr: 17 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 17 34 0 9 0 0 9 9 0 0 9 9 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 17 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _