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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL7
All Species:
25.45
Human Site:
Y269
Identified Species:
62.22
UniProt:
Q8IXQ5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXQ5
NP_001026880.2
586
65992
Y269
M
V
I
S
G
M
R
Y
H
L
L
S
P
E
D
Chimpanzee
Pan troglodytes
XP_517523
593
66157
Y285
Y
L
I
E
A
M
K
Y
H
L
L
P
T
E
Q
Rhesus Macaque
Macaca mulatta
XP_001101595
586
66000
Y269
M
V
I
S
G
M
R
Y
H
L
L
S
P
E
D
Dog
Lupus familis
XP_532490
538
60721
D228
Y
H
L
L
S
P
E
D
R
E
E
L
V
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUL5
586
65919
Y269
M
V
I
S
G
M
R
Y
H
L
L
S
P
E
D
Rat
Rattus norvegicus
Q5XHZ6
586
65951
Y269
M
V
I
S
G
M
R
Y
H
L
L
S
P
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513755
600
67864
Y283
M
V
I
S
G
M
R
Y
H
L
L
S
P
E
D
Chicken
Gallus gallus
Q5ZI33
586
66177
Y269
M
V
I
S
G
M
R
Y
H
L
L
S
P
E
D
Frog
Xenopus laevis
Q6NRH0
564
63190
F254
L
V
D
E
A
K
K
F
H
L
R
P
E
L
R
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
F254
L
V
D
E
A
K
K
F
H
L
R
P
E
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.7
99.8
91.6
N.A.
97.7
97.9
N.A.
92.8
98.1
32.4
33.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
53.4
100
91.8
N.A.
98.9
99.1
N.A.
94.8
99.4
50.1
49.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
100
6.6
N.A.
100
100
N.A.
100
100
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
13.3
N.A.
100
100
N.A.
100
100
40
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
0
0
10
0
0
0
0
0
0
60
% D
% Glu:
0
0
0
30
0
0
10
0
0
10
10
0
20
80
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
90
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
20
30
0
0
0
0
0
0
0
0
% K
% Leu:
20
10
10
10
0
0
0
0
0
90
70
10
0
20
0
% L
% Met:
60
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
30
60
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
60
0
10
0
20
0
0
0
20
% R
% Ser:
0
0
0
60
10
0
0
0
0
0
0
60
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
80
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _