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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHOT1
All Species:
32.42
Human Site:
Y465
Identified Species:
50.95
UniProt:
Q8IXI2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXI2
NP_001028738.1
618
70784
Y465
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Chimpanzee
Pan troglodytes
XP_511399
695
80129
Y469
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Rhesus Macaque
Macaca mulatta
XP_001109912
830
94570
Y604
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Dog
Lupus familis
XP_867966
631
72105
Y478
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG51
631
72223
Y478
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Rat
Rattus norvegicus
Q7TSA0
622
69135
G466
I
N
T
V
R
V
S
G
Q
E
K
Y
L
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511136
687
78991
Y467
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Chicken
Gallus gallus
Q5ZM73
619
70876
Y466
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Frog
Xenopus laevis
NP_001121318
618
70967
Y465
A
I
N
P
V
Y
V
Y
G
Q
E
K
Y
L
L
Zebra Danio
Brachydanio rerio
Q6NVC5
619
71179
G466
I
S
T
T
Y
V
Y
G
Q
E
K
Y
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMX7
652
73757
E496
S
V
Q
V
Y
G
Q
E
K
H
L
I
L
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94263
625
70204
K472
V
I
N
R
V
R
V
K
E
E
S
K
Y
L
L
Sea Urchin
Strong. purpuratus
XP_791124
583
66070
R431
R
C
N
V
I
G
P
R
G
A
G
K
S
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39722
662
75132
Y498
E
L
K
G
G
K
Q
Y
Y
L
I
L
Q
E
L
Red Bread Mold
Neurospora crassa
Q7RZA2
629
70228
C473
E
L
Q
G
G
K
Q
C
Y
L
I
L
E
E
L
Conservation
Percent
Protein Identity:
100
87
74.3
96.6
N.A.
95.8
58
N.A.
85.5
93.8
85.5
85.9
N.A.
50.6
N.A.
44
59.5
Protein Similarity:
100
88.1
74.4
97.4
N.A.
97.6
75
N.A.
87.9
97.7
94.1
94.8
N.A.
68.8
N.A.
64.1
72.9
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
93.3
20
N.A.
0
N.A.
53.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
100
93.3
33.3
N.A.
13.3
N.A.
60
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.1
34.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.8
53.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% A
% Cys:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
14
0
0
0
0
0
0
7
7
20
54
0
7
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
14
14
14
0
14
60
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
14
60
0
0
7
0
0
0
0
0
14
7
0
7
0
% I
% Lys:
0
0
7
0
0
14
0
7
7
0
14
67
0
0
0
% K
% Leu:
0
14
0
0
0
0
0
0
0
14
7
14
20
67
87
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
67
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
14
0
0
0
20
0
14
54
0
0
7
0
0
% Q
% Arg:
7
0
0
7
7
7
0
7
0
0
0
0
0
7
0
% R
% Ser:
7
7
0
0
0
0
7
0
0
0
7
0
7
0
0
% S
% Thr:
0
0
14
54
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
20
60
14
60
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
14
54
7
60
14
0
0
14
60
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _