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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO1L1
All Species:
2.42
Human Site:
S445
Identified Species:
5.33
UniProt:
Q8IX06
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IX06
NP_758439
675
73855
S445
H
W
G
R
V
R
S
S
Q
V
A
G
G
R
V
Chimpanzee
Pan troglodytes
P48778
690
75343
T458
N
T
R
F
S
G
V
T
E
A
D
V
A
K
T
Rhesus Macaque
Macaca mulatta
XP_001096198
1215
131336
K960
T
A
E
E
K
R
P
K
D
S
S
C
R
T
C
Dog
Lupus familis
XP_533958
1655
172531
K1400
T
A
E
E
K
K
P
K
D
S
S
C
R
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT28
1213
130772
K958
T
A
E
E
K
K
P
K
D
P
S
C
R
I
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516921
311
35095
G91
L
R
F
E
V
A
G
G
L
E
T
R
Y
S
C
Chicken
Gallus gallus
XP_425887
1229
134673
T974
T
A
E
E
K
K
S
T
D
S
S
C
R
I
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001119888
1207
134661
K949
V
V
H
N
L
P
E
K
K
N
N
D
P
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733234
937
105604
K671
G
Y
P
R
P
G
D
K
R
G
S
A
V
I
R
Honey Bee
Apis mellifera
XP_392195
1145
130995
C614
A
H
P
S
A
A
A
C
V
T
R
Q
I
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790674
215
24370
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
36.2
27.4
N.A.
35
N.A.
N.A.
27.5
31.5
N.A.
29.6
N.A.
26.2
24.9
N.A.
20
Protein Similarity:
100
82.6
43.5
32.8
N.A.
42.9
N.A.
N.A.
35.4
41.7
N.A.
40
N.A.
39.2
38.9
N.A.
26.6
P-Site Identity:
100
0
6.6
0
N.A.
0
N.A.
N.A.
6.6
6.6
N.A.
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
26.6
13.3
13.3
N.A.
13.3
N.A.
N.A.
6.6
26.6
N.A.
13.3
N.A.
26.6
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
37
0
0
10
19
10
0
0
10
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
37
0
0
46
% C
% Asp:
0
0
0
0
0
0
10
0
37
0
10
10
0
0
0
% D
% Glu:
0
0
37
46
0
0
10
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
0
10
0
0
19
10
10
0
10
0
10
10
10
0
% G
% His:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
37
10
% I
% Lys:
0
0
0
0
37
28
0
46
10
0
0
0
0
10
0
% K
% Leu:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
19
0
10
10
28
0
0
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
10
10
19
0
19
0
0
10
0
10
10
37
10
10
% R
% Ser:
0
0
0
10
10
0
19
10
0
28
46
0
0
10
10
% S
% Thr:
37
10
0
0
0
0
0
19
0
10
10
0
0
10
10
% T
% Val:
10
10
0
0
19
0
10
0
10
10
0
10
10
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _