KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SULF2
All Species:
16.97
Human Site:
Y527
Identified Species:
33.94
UniProt:
Q8IWU5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWU5
NP_001155313.1
870
100455
Y527
K
K
L
F
K
K
K
Y
K
A
S
Y
V
R
S
Chimpanzee
Pan troglodytes
XP_514701
348
40666
K55
A
P
E
D
Q
D
D
K
D
G
G
D
F
S
G
Rhesus Macaque
Macaca mulatta
XP_001106412
1204
136421
Y861
K
K
L
F
K
K
K
Y
K
A
S
Y
A
R
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFG0
875
100451
Y532
R
K
L
F
K
K
K
Y
K
T
S
Y
A
R
N
Rat
Rattus norvegicus
Q8VI60
870
100841
Y533
R
N
Q
G
T
P
K
Y
K
P
R
F
V
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510791
860
97763
D545
Q
K
W
Q
C
L
E
D
A
A
G
K
L
R
I
Chicken
Gallus gallus
XP_417386
877
102190
Y529
K
L
F
S
K
K
K
Y
K
P
S
Y
A
R
N
Frog
Xenopus laevis
NP_001088414
872
101568
Y529
K
L
L
T
K
K
K
Y
K
A
S
Y
Q
R
N
Zebra Danio
Brachydanio rerio
NP_001003833
885
102377
M543
K
L
F
S
K
K
K
M
K
S
L
K
S
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEX0
1114
127285
Q592
F
H
L
Q
L
E
H
Q
L
A
A
M
P
R
K
Honey Bee
Apis mellifera
XP_393715
1436
166412
F682
E
E
D
D
E
D
F
F
Q
E
L
D
S
L
A
Nematode Worm
Caenorhab. elegans
Q21376
709
83765
D416
P
K
L
K
K
I
R
D
R
Y
I
K
Q
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
71.5
N.A.
N.A.
93.9
65.6
N.A.
56.4
86
81.7
74.1
N.A.
34.8
30
38.6
N.A.
Protein Similarity:
100
37.5
71.8
N.A.
N.A.
96
79.6
N.A.
69.8
92.5
90.8
84.8
N.A.
50.9
42.4
55.6
N.A.
P-Site Identity:
100
0
93.3
N.A.
N.A.
73.3
26.6
N.A.
20
60
73.3
40
N.A.
20
0
20
N.A.
P-Site Similarity:
100
6.6
93.3
N.A.
N.A.
86.6
46.6
N.A.
40
66.6
80
46.6
N.A.
33.3
40
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
9
42
9
0
25
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
17
0
17
9
17
9
0
0
17
0
0
0
% D
% Glu:
9
9
9
0
9
9
9
0
0
9
0
0
0
0
0
% E
% Phe:
9
0
17
25
0
0
9
9
0
0
0
9
9
9
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
9
17
0
0
0
9
% G
% His:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
9
% I
% Lys:
42
42
0
9
59
50
59
9
59
0
0
25
0
9
17
% K
% Leu:
0
25
50
0
9
9
0
0
9
0
17
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
25
% N
% Pro:
9
9
0
0
0
9
0
0
0
17
0
0
9
0
0
% P
% Gln:
9
0
9
17
9
0
0
9
9
0
0
0
17
0
0
% Q
% Arg:
17
0
0
0
0
0
9
0
9
0
9
0
0
59
0
% R
% Ser:
0
0
0
17
0
0
0
0
0
9
42
0
17
9
25
% S
% Thr:
0
0
0
9
9
0
0
0
0
9
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
9
0
42
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _