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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SULF2 All Species: 16.97
Human Site: S858 Identified Species: 33.94
UniProt: Q8IWU5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWU5 NP_001155313.1 870 100455 S858 P E M K R P S S K S L G Q L W
Chimpanzee Pan troglodytes XP_514701 348 40666 L339 K R P S S K S L G Q L W E G W
Rhesus Macaque Macaca mulatta XP_001106412 1204 136421 S1192 P E M K R P S S K S L G Q L W
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8CFG0 875 100451 S863 P E M K R P S S K S L G Q L W
Rat Rattus norvegicus Q8VI60 870 100841 D858 T K E G G N Y D P H R G Q L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510791 860 97763 E850 A L Q L D T H E P L L L K L V
Chicken Gallus gallus XP_417386 877 102190 S865 D V K R P S S S K S L G Q L W
Frog Xenopus laevis NP_001088414 872 101568 K861 K M K R P S S K S L G Q L W D
Zebra Danio Brachydanio rerio NP_001003833 885 102377 S873 P K V R K P V S K S L G Q I W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEX0 1114 127285 A1049 K H S P L A G A V G N Y A F V
Honey Bee Apis mellifera XP_393715 1436 166412 L1386 D M F V P S T L Q I I R E S E
Nematode Worm Caenorhab. elegans Q21376 709 83765 S700 D L R V N E K S F L T Y Q P E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 71.5 N.A. N.A. 93.9 65.6 N.A. 56.4 86 81.7 74.1 N.A. 34.8 30 38.6 N.A.
Protein Similarity: 100 37.5 71.8 N.A. N.A. 96 79.6 N.A. 69.8 92.5 90.8 84.8 N.A. 50.9 42.4 55.6 N.A.
P-Site Identity: 100 20 100 N.A. N.A. 100 26.6 N.A. 13.3 60 6.6 60 N.A. 0 0 13.3 N.A.
P-Site Similarity: 100 26.6 100 N.A. N.A. 100 33.3 N.A. 20 66.6 13.3 93.3 N.A. 6.6 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 9 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 0 0 9 0 0 9 0 0 0 0 0 0 9 % D
% Glu: 0 25 9 0 0 9 0 9 0 0 0 0 17 0 17 % E
% Phe: 0 0 9 0 0 0 0 0 9 0 0 0 0 9 0 % F
% Gly: 0 0 0 9 9 0 9 0 9 9 9 50 0 9 0 % G
% His: 0 9 0 0 0 0 9 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 9 0 0 9 0 % I
% Lys: 25 17 17 25 9 9 9 9 42 0 0 0 9 0 0 % K
% Leu: 0 17 0 9 9 0 0 17 0 25 59 9 9 50 0 % L
% Met: 0 17 25 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 9 0 0 0 0 % N
% Pro: 34 0 9 9 25 34 0 0 17 0 0 0 0 9 0 % P
% Gln: 0 0 9 0 0 0 0 0 9 9 0 9 59 0 0 % Q
% Arg: 0 9 9 25 25 0 0 0 0 0 9 9 0 0 0 % R
% Ser: 0 0 9 9 9 25 50 50 9 42 0 0 0 9 0 % S
% Thr: 9 0 0 0 0 9 9 0 0 0 9 0 0 0 0 % T
% Val: 0 9 9 17 0 0 9 0 9 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 59 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _