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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H7A
All Species:
25.15
Human Site:
Y499
Identified Species:
61.48
UniProt:
Q8IWR0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWR0
NP_054872.2
971
110538
Y499
P
R
P
T
K
T
N
Y
E
G
P
Y
Y
I
C
Chimpanzee
Pan troglodytes
XP_001144154
971
110503
Y499
P
R
P
T
K
T
N
Y
E
G
P
Y
Y
I
C
Rhesus Macaque
Macaca mulatta
XP_001106316
971
110560
Y499
P
R
P
T
K
T
N
Y
E
G
P
Y
Y
I
C
Dog
Lupus familis
XP_536973
971
109950
Y499
P
R
P
T
K
T
N
Y
E
G
P
Y
Y
I
C
Cat
Felis silvestris
Mouse
Mus musculus
NP_666043
970
110774
Y498
P
R
P
T
K
T
N
Y
E
G
P
Y
Y
I
C
Rat
Rattus norvegicus
NP_001101732
706
79350
E314
L
N
A
F
S
V
T
E
S
T
R
D
L
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506253
973
109938
Y500
P
R
P
T
K
T
H
Y
E
G
P
Y
Y
I
C
Chicken
Gallus gallus
XP_414739
952
107142
A477
Y
Y
I
C
K
D
V
A
A
E
E
E
C
R
Y
Frog
Xenopus laevis
NP_001086721
916
102866
I481
F
A
Y
S
Q
E
E
I
D
V
W
T
Q
E
R
Zebra Danio
Brachydanio rerio
NP_998599
983
112033
Y509
R
P
R
P
K
N
Q
Y
M
G
P
Y
Y
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.2
94.3
N.A.
85.2
63
N.A.
76.7
71.6
52.3
52.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.5
97.2
N.A.
92.7
67.8
N.A.
86
82.3
64.5
69.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
6.6
0
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
100
6.6
20
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
70
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
10
60
10
10
10
0
10
0
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
10
0
0
0
0
0
70
0
% I
% Lys:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
50
0
0
0
0
0
0
0
0
% N
% Pro:
60
10
60
10
0
0
0
0
0
0
70
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
10
60
10
0
0
0
0
0
0
0
10
0
0
10
10
% R
% Ser:
0
0
0
10
10
0
0
0
10
0
0
0
0
10
0
% S
% Thr:
0
0
0
60
0
60
10
0
0
10
0
10
0
0
10
% T
% Val:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
10
10
0
0
0
0
70
0
0
0
70
70
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _