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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRSK2 All Species: 5.76
Human Site: Y717 Identified Species: 14.07
UniProt: Q8IWQ3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWQ3 NP_003948.2 736 81633 Y717 G P G G D A E Y P T G K D T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850919 676 75195 R657 G P G G D A E R P T A Q D A A
Cat Felis silvestris
Mouse Mus musculus Q69Z98 735 81715 Y716 G P G G D T E Y P M G K D M A
Rat Rattus norvegicus Q8VHF0 797 88733 S768 V C K L P R L S L N G V R F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9IA88 798 88848 S763 T T F S Q Q Q S F S A Q S P S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 E1108 D D A Y E Q V E P M S G M S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648814 861 95238 S833 G S P I A V R S N S E T A E H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 K1030 T I W S K L S K L T R R D H N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 P494 D I Q R V N G P Q F L F L D L
Baker's Yeast Sacchar. cerevisiae P34244 1518 169574 E1316 G G G K I K E E H T K L D N K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 89.8 N.A. 97.9 25.4 N.A. N.A. 27.4 N.A. 25.1 N.A. 50.9 N.A. 23.1 N.A.
Protein Similarity: 100 N.A. N.A. 90.3 N.A. 98.7 43.2 N.A. N.A. 43.9 N.A. 37.9 N.A. 63.5 N.A. 37.3 N.A.
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 80 6.6 N.A. N.A. 0 N.A. 6.6 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 N.A. N.A. 80 N.A. 80 6.6 N.A. N.A. 26.6 N.A. 20 N.A. 13.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.8 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 33.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 20 0 0 0 0 20 0 10 10 30 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 10 0 0 30 0 0 0 0 0 0 0 50 10 0 % D
% Glu: 0 0 0 0 10 0 40 20 0 0 10 0 0 10 0 % E
% Phe: 0 0 10 0 0 0 0 0 10 10 0 10 0 10 0 % F
% Gly: 50 10 40 30 0 0 10 0 0 0 30 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % H
% Ile: 0 20 0 10 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 10 10 10 0 10 0 0 10 20 0 0 20 % K
% Leu: 0 0 0 10 0 10 10 0 20 0 10 10 10 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 20 0 0 10 10 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 10 0 0 0 10 10 % N
% Pro: 0 30 10 0 10 0 0 10 40 0 0 0 0 10 0 % P
% Gln: 0 0 10 0 10 20 10 0 10 0 0 20 0 0 0 % Q
% Arg: 0 0 0 10 0 10 10 10 0 0 10 10 10 0 0 % R
% Ser: 0 10 0 20 0 0 10 30 0 20 10 0 10 10 10 % S
% Thr: 20 10 0 0 0 10 0 0 0 40 0 10 0 10 0 % T
% Val: 10 0 0 0 10 10 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 20 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _