Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRSK2 All Species: 4.24
Human Site: S704 Identified Species: 10.37
UniProt: Q8IWQ3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWQ3 NP_003948.2 736 81633 S704 A H G P L G D S A A A G P G P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850919 676 75195 S644 A P G P L G D S A A A G P G P
Cat Felis silvestris
Mouse Mus musculus Q69Z98 735 81715 G703 R S A H G P L G D S A A A G P
Rat Rattus norvegicus Q8VHF0 797 88733 V755 D G H A E S L V Q W E M E V C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9IA88 798 88848 N750 T H L Y I S S N V S P V G T T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 H1095 R G A L Q R H H T I Q T C D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648814 861 95238 N820 T T N N N N A N P V D I P G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 A1017 I G A T G P S A N N A E A T I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 E481 L Q L Y K A R E E K Y L L D I
Baker's Yeast Sacchar. cerevisiae P34244 1518 169574 E1303 M L F D E E E E E S K K V G G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 89.8 N.A. 97.9 25.4 N.A. N.A. 27.4 N.A. 25.1 N.A. 50.9 N.A. 23.1 N.A.
Protein Similarity: 100 N.A. N.A. 90.3 N.A. 98.7 43.2 N.A. N.A. 43.9 N.A. 37.9 N.A. 63.5 N.A. 37.3 N.A.
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 20 0 N.A. N.A. 6.6 N.A. 0 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 26.6 0 N.A. N.A. 26.6 N.A. 0 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.8 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 33.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 30 10 0 10 10 10 20 20 40 10 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % C
% Asp: 10 0 0 10 0 0 20 0 10 0 10 0 0 20 10 % D
% Glu: 0 0 0 0 20 10 10 20 20 0 10 10 10 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 30 20 0 20 20 0 10 0 0 0 20 10 50 10 % G
% His: 0 20 10 10 0 0 10 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 0 0 0 10 0 10 0 0 20 % I
% Lys: 0 0 0 0 10 0 0 0 0 10 10 10 0 0 0 % K
% Leu: 10 10 20 10 20 0 20 0 0 0 0 10 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 10 10 10 10 0 20 10 10 0 0 0 0 0 % N
% Pro: 0 10 0 20 0 20 0 0 10 0 10 0 30 0 30 % P
% Gln: 0 10 0 0 10 0 0 0 10 0 10 0 0 0 0 % Q
% Arg: 20 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 20 20 20 0 30 0 0 0 0 10 % S
% Thr: 20 10 0 10 0 0 0 0 10 0 0 10 0 20 10 % T
% Val: 0 0 0 0 0 0 0 10 10 10 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 20 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _