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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR125
All Species:
22.12
Human Site:
Y950
Identified Species:
60.83
UniProt:
Q8IWK6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWK6
NP_660333.2
1321
146151
Y950
K
R
H
P
E
R
K
Y
E
L
K
E
P
T
E
Chimpanzee
Pan troglodytes
XP_001164297
1320
146164
Y949
K
R
H
P
E
R
K
Y
E
L
K
E
P
T
E
Rhesus Macaque
Macaca mulatta
XP_001104904
1319
146032
Y948
K
R
H
P
E
R
K
Y
E
L
K
E
P
T
E
Dog
Lupus familis
XP_545977
1318
145233
Y952
R
R
H
P
E
R
R
Y
E
L
K
E
P
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT36
1310
144705
Y939
K
R
H
P
E
R
K
Y
E
L
K
E
P
T
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513419
1289
142668
F920
K
R
H
P
E
R
K
F
E
L
K
E
P
T
E
Chicken
Gallus gallus
XP_420763
1322
146745
Y951
K
R
H
P
E
R
K
Y
E
L
K
E
P
A
E
Frog
Xenopus laevis
NP_001083670
1306
144699
K942
R
R
Q
P
A
E
Q
K
D
V
P
E
T
N
D
Zebra Danio
Brachydanio rerio
XP_001343104
1229
135194
L873
S
L
T
L
Y
A
A
L
W
V
F
G
A
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.8
N.A.
92.6
N.A.
N.A.
87.5
85.4
42.2
57.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.3
87.9
N.A.
95.3
N.A.
N.A.
92.1
92.8
60.6
70
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
100
N.A.
N.A.
93.3
93.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
100
93.3
53.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
12
0
0
0
0
0
12
23
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% D
% Glu:
0
0
0
0
78
12
0
0
78
0
0
89
0
0
78
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
67
0
0
0
0
0
67
12
0
0
78
0
0
0
0
% K
% Leu:
0
12
0
12
0
0
0
12
0
78
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
89
0
0
0
0
0
0
12
0
78
0
0
% P
% Gln:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
23
89
0
0
0
78
12
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
12
56
0
% T
% Val:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _