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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR125
All Species:
24.24
Human Site:
S1067
Identified Species:
66.67
UniProt:
Q8IWK6
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWK6
NP_660333.2
1321
146151
S1067
T
C
C
P
G
R
S
S
Y
S
V
Q
V
N
V
Chimpanzee
Pan troglodytes
XP_001164297
1320
146164
S1066
T
C
C
P
G
R
S
S
Y
S
V
Q
V
N
V
Rhesus Macaque
Macaca mulatta
XP_001104904
1319
146032
S1065
T
C
C
P
G
R
S
S
Y
S
V
Q
V
N
V
Dog
Lupus familis
XP_545977
1318
145233
A1069
T
C
C
P
G
R
G
A
Y
S
M
Q
V
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT36
1310
144705
S1056
M
C
C
P
G
R
S
S
Y
S
V
Q
V
N
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513419
1289
142668
S1037
T
C
C
P
G
R
S
S
Y
S
V
Q
V
D
I
Chicken
Gallus gallus
XP_420763
1322
146745
T1068
T
C
C
P
G
R
S
T
Y
S
V
Q
V
N
V
Frog
Xenopus laevis
NP_001083670
1306
144699
S1057
S
W
F
A
C
C
P
S
Y
T
E
A
L
P
I
Zebra Danio
Brachydanio rerio
XP_001343104
1229
135194
N981
K
S
A
P
S
L
R
N
S
T
Q
G
C
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.8
N.A.
92.6
N.A.
N.A.
87.5
85.4
42.2
57.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.3
87.9
N.A.
95.3
N.A.
N.A.
92.1
92.8
60.6
70
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
93.3
N.A.
N.A.
86.6
93.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
100
100
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
0
12
0
0
0
12
0
0
0
% A
% Cys:
0
78
78
0
12
12
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
78
0
12
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
12
% L
% Met:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
56
0
% N
% Pro:
0
0
0
89
0
0
12
0
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
78
0
0
0
% Q
% Arg:
0
0
0
0
0
78
12
0
0
0
0
0
0
0
0
% R
% Ser:
12
12
0
0
12
0
67
67
12
78
0
0
0
0
0
% S
% Thr:
67
0
0
0
0
0
0
12
0
23
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
67
0
78
0
67
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _