KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD6L
All Species:
20.91
Human Site:
Y553
Identified Species:
65.71
UniProt:
Q8IWD5
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWD5
NP_689812.2
586
64005
Y553
P
R
E
R
K
I
K
Y
S
K
L
L
S
M
E
Chimpanzee
Pan troglodytes
XP_511849
586
64125
Y553
P
Q
E
R
K
I
K
Y
S
K
L
L
S
M
E
Rhesus Macaque
Macaca mulatta
XP_001113290
586
64020
Y553
P
Q
E
R
K
I
K
Y
S
K
L
L
S
M
E
Dog
Lupus familis
XP_546614
572
60587
Y539
P
Q
E
Q
K
I
N
Y
S
K
L
L
V
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3N2
586
63412
Y550
P
Q
E
Q
R
I
N
Y
S
K
L
L
A
M
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XGZ9
614
68954
Y578
P
N
I
K
K
I
N
Y
S
R
L
L
A
A
D
Zebra Danio
Brachydanio rerio
Q6DBX0
542
59697
T510
S
R
L
L
A
A
D
T
E
V
S
E
S
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788637
330
36237
E298
K
L
L
Q
S
D
M
E
M
D
M
K
G
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
91.8
72.3
N.A.
68.9
N.A.
N.A.
N.A.
N.A.
40.8
36.3
N.A.
N.A.
N.A.
N.A.
22.5
Protein Similarity:
100
98.6
94
79.3
N.A.
78.8
N.A.
N.A.
N.A.
N.A.
57
53.7
N.A.
N.A.
N.A.
N.A.
32.9
P-Site Identity:
100
93.3
93.3
73.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
46.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
73.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
13
0
0
0
0
0
0
25
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
13
0
0
13
0
0
0
0
13
% D
% Glu:
0
0
63
0
0
0
0
13
13
0
0
13
0
13
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
75
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
0
13
63
0
38
0
0
63
0
13
0
0
0
% K
% Leu:
0
13
25
13
0
0
0
0
0
0
75
75
0
0
0
% L
% Met:
0
0
0
0
0
0
13
0
13
0
13
0
0
63
0
% M
% Asn:
0
13
0
0
0
0
38
0
0
0
0
0
0
0
0
% N
% Pro:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
50
0
38
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
25
0
38
13
0
0
0
0
13
0
0
0
0
0
% R
% Ser:
13
0
0
0
13
0
0
0
75
0
13
0
50
0
13
% S
% Thr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
13
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _