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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A9
All Species:
10.61
Human Site:
T314
Identified Species:
29.17
UniProt:
Q8IVM8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVM8
NP_543142.2
553
62169
T314
G
M
K
N
A
R
D
T
L
T
L
E
I
L
K
Chimpanzee
Pan troglodytes
XP_001160644
553
62173
T314
G
M
K
N
A
R
D
T
L
T
L
E
I
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533255
552
61678
A314
G
R
K
N
A
G
E
A
L
T
M
E
V
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFZ5
553
60176
T314
R
R
K
A
E
G
D
T
L
T
M
E
V
L
R
Rat
Rattus norvegicus
Q3ZAV1
553
60226
T314
R
R
K
A
E
A
D
T
L
T
V
E
V
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507099
556
61556
G313
N
R
K
A
V
A
K
G
C
L
T
I
E
M
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J54
558
62434
K308
G
K
E
E
E
G
E
K
I
T
L
E
S
M
R
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
K311
G
R
S
A
E
G
D
K
I
D
L
E
M
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
E301
E
V
P
N
E
I
Y
E
Q
L
V
D
E
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
63.6
N.A.
43.5
44.1
N.A.
43.7
N.A.
39.2
37.5
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
N.A.
77.2
N.A.
58.5
58.7
N.A.
60.9
N.A.
59.3
57.6
N.A.
50.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
53.3
N.A.
46.6
46.6
N.A.
6.6
N.A.
26.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
80
N.A.
66.6
66.6
N.A.
13.3
N.A.
60
53.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
34
23
0
12
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
56
0
0
12
0
12
0
0
0
% D
% Glu:
12
0
12
12
56
0
23
12
0
0
0
78
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
56
0
0
0
0
45
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
23
0
0
12
23
0
0
% I
% Lys:
0
12
67
0
0
0
12
23
0
0
0
0
0
0
23
% K
% Leu:
0
0
0
0
0
0
0
0
56
23
45
0
0
67
12
% L
% Met:
0
23
0
0
0
0
0
0
0
0
23
0
12
23
0
% M
% Asn:
12
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% Q
% Arg:
23
56
0
0
0
23
0
0
0
0
0
0
0
0
45
% R
% Ser:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
45
0
67
12
0
0
0
0
% T
% Val:
0
12
0
0
12
0
0
0
0
0
23
0
34
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _