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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC49
All Species:
25.45
Human Site:
T275
Identified Species:
50.91
UniProt:
Q8IUZ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUZ0
NP_060161.2
686
78894
T275
S
S
S
L
S
D
I
T
F
D
G
N
P
I
A
Chimpanzee
Pan troglodytes
XP_001174991
686
78876
T275
S
S
S
L
S
D
I
T
F
D
G
N
P
I
A
Rhesus Macaque
Macaca mulatta
XP_001089082
686
78845
T275
S
S
S
L
S
D
I
T
F
D
G
N
P
I
A
Dog
Lupus familis
XP_544751
686
78905
T275
S
S
S
L
S
D
I
T
F
D
G
N
P
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91YK0
686
78858
T275
S
T
S
L
S
D
I
T
F
D
G
N
P
I
A
Rat
Rattus norvegicus
Q5HZV9
360
41278
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510696
262
28678
Chicken
Gallus gallus
XP_413778
851
95440
T443
S
S
S
L
S
D
I
T
L
D
G
N
P
I
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q32PL1
345
39366
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397479
766
87590
T284
A
L
Q
L
R
E
I
T
I
D
G
N
P
I
T
Nematode Worm
Caenorhab. elegans
P45969
326
37341
Sea Urchin
Strong. purpuratus
XP_001202596
611
68763
D243
D
D
I
S
C
L
A
D
S
T
S
L
I
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
92.7
N.A.
89.3
20.5
N.A.
27.5
60
N.A.
20.1
N.A.
N.A.
30.6
20.7
44.9
Protein Similarity:
100
100
99.7
97.2
N.A.
96.5
35.5
N.A.
33.3
70.5
N.A.
35.1
N.A.
N.A.
48.4
33
62.2
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
0
93.3
N.A.
0
N.A.
N.A.
53.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
0
93.3
N.A.
0
N.A.
N.A.
66.6
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
50
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
50
0
9
0
59
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
59
0
9
0
0
0
9
59
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
59
0
9
0
0
9
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
59
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
59
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
42
50
9
50
0
0
0
9
0
9
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
59
0
9
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _