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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLVS1
All Species:
24.85
Human Site:
S327
Identified Species:
49.7
UniProt:
Q8IUQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUQ0
NP_775790.1
354
40788
S327
S
P
K
L
M
K
R
S
Q
S
V
V
E
A
G
Chimpanzee
Pan troglodytes
XP_001158960
304
35294
H278
S
D
E
N
D
Y
T
H
T
S
Y
N
A
M
H
Rhesus Macaque
Macaca mulatta
XP_001091304
354
40742
S327
S
P
K
L
M
K
R
S
Q
S
V
V
E
A
G
Dog
Lupus familis
XP_544098
354
40730
S327
S
P
K
P
M
K
R
S
Q
S
V
V
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4C9
354
40595
S327
S
P
K
P
M
K
R
S
Q
S
V
V
E
A
G
Rat
Rattus norvegicus
P41034
278
31827
M252
Y
G
G
N
E
S
S
M
E
D
I
C
Q
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513318
344
39097
L317
H
L
K
A
R
L
A
L
R
G
L
L
G
R
Q
Chicken
Gallus gallus
XP_419223
332
38227
S305
S
P
K
P
M
K
R
S
Q
S
V
V
E
A
G
Frog
Xenopus laevis
Q5M7E1
332
38511
S305
S
P
K
Y
M
K
R
S
H
S
V
V
E
P
G
Zebra Danio
Brachydanio rerio
Q5SPP0
329
38101
S300
S
P
K
T
M
K
R
S
Q
S
V
V
E
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396934
371
41463
K314
S
G
N
I
E
S
H
K
R
N
E
A
D
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCU1
409
46492
A342
G
W
D
L
E
Y
S
A
E
F
V
P
N
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
99.7
98.8
N.A.
97.1
27.3
N.A.
62.7
88.6
84.4
74.5
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
100
85.8
100
99.1
N.A.
98.3
44.9
N.A.
68.3
90.6
88.6
82.1
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
0
N.A.
6.6
93.3
80
86.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
93.3
20
N.A.
26.6
93.3
80
86.6
N.A.
N.A.
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
9
0
0
0
9
9
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
9
0
9
0
0
0
0
9
0
0
9
0
0
% D
% Glu:
0
0
9
0
25
0
0
0
17
0
9
0
59
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
17
9
0
0
0
0
0
0
9
0
0
9
0
59
% G
% His:
9
0
0
0
0
0
9
9
9
0
0
0
0
0
9
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
0
67
0
0
59
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
25
0
9
0
9
0
0
9
9
0
0
0
% L
% Met:
0
0
0
0
59
0
0
9
0
0
0
0
0
9
0
% M
% Asn:
0
0
9
17
0
0
0
0
0
9
0
9
9
0
0
% N
% Pro:
0
59
0
25
0
0
0
0
0
0
0
9
0
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
0
0
0
9
0
9
% Q
% Arg:
0
0
0
0
9
0
59
0
17
0
0
0
0
9
0
% R
% Ser:
75
0
0
0
0
17
17
59
0
67
0
0
0
9
0
% S
% Thr:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
67
59
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
0
9
0
17
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _