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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLVS1
All Species:
26.06
Human Site:
S154
Identified Species:
52.12
UniProt:
Q8IUQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUQ0
NP_775790.1
354
40788
S154
N
W
D
Q
S
R
N
S
F
T
D
I
L
R
A
Chimpanzee
Pan troglodytes
XP_001158960
304
35294
H113
G
V
L
E
N
R
D
H
Y
G
R
K
I
L
L
Rhesus Macaque
Macaca mulatta
XP_001091304
354
40742
S154
N
W
D
Q
S
R
N
S
F
T
D
I
L
R
A
Dog
Lupus familis
XP_544098
354
40730
S154
N
W
D
Q
S
R
N
S
F
T
D
I
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4C9
354
40595
S154
N
W
D
Q
S
R
N
S
F
T
D
I
L
R
A
Rat
Rattus norvegicus
P41034
278
31827
L87
C
P
E
L
S
A
D
L
H
P
R
S
I
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513318
344
39097
D150
M
F
K
N
F
K
A
D
D
P
G
I
K
R
A
Chicken
Gallus gallus
XP_419223
332
38227
S132
N
W
D
Q
S
R
N
S
F
I
D
I
L
R
A
Frog
Xenopus laevis
Q5M7E1
332
38511
S132
N
W
D
Q
S
R
N
S
F
V
D
I
L
R
A
Zebra Danio
Brachydanio rerio
Q5SPP0
329
38101
T132
N
W
D
Q
S
R
Y
T
F
V
D
I
L
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396934
371
41463
P141
Q
W
D
P
I
A
V
P
A
L
S
V
Q
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCU1
409
46492
N170
F
G
D
E
E
K
L
N
K
F
L
R
W
R
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
99.7
98.8
N.A.
97.1
27.3
N.A.
62.7
88.6
84.4
74.5
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
100
85.8
100
99.1
N.A.
98.3
44.9
N.A.
68.3
90.6
88.6
82.1
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
20
93.3
93.3
80
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
26.6
N.A.
33.3
93.3
93.3
86.6
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
9
0
9
0
0
0
0
0
75
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
75
0
0
0
17
9
9
0
59
0
0
0
0
% D
% Glu:
0
0
9
17
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
9
0
0
9
0
0
0
59
9
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
9
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
0
67
17
0
0
% I
% Lys:
0
0
9
0
0
17
0
0
9
0
0
9
9
0
0
% K
% Leu:
0
0
9
9
0
0
9
9
0
9
9
0
59
17
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
59
0
0
9
9
0
50
9
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
9
0
17
0
0
0
0
0
% P
% Gln:
9
0
0
59
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
67
0
0
0
0
17
9
0
84
0
% R
% Ser:
0
0
0
0
67
0
0
50
0
0
9
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
34
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
9
0
0
17
0
9
0
0
9
% V
% Trp:
0
67
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _