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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPAS4 All Species: 19.09
Human Site: T536 Identified Species: 52.5
UniProt: Q8IUM7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUM7 NP_849195.2 802 87117 T536 E Q L T P P S T A F Q A H L D
Chimpanzee Pan troglodytes A2T6X9 766 85495 E507 K A S P E S R E A Y E N S M P
Rhesus Macaque Macaca mulatta XP_001110331 802 87107 T536 E Q L T P P S T A F Q A H L D
Dog Lupus familis XP_540832 800 86767 T534 E Q L T P P S T A F Q A H L N
Cat Felis silvestris
Mouse Mus musculus Q8BGD7 802 87267 T536 E Q L T P P S T A F Q A H L N
Rat Rattus norvegicus Q8CJH6 802 87299 T536 E Q L T P P S T A F Q A H L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9YIB9 811 90524 F548 D T E A K N P F S T Q E T D L
Frog Xenopus laevis Q9I8A9 805 90946 S521 E Y C F D V D S E M A S E F K
Zebra Danio Brachydanio rerio Q1ECW2 933 100083 P553 T T A P S L S P S A P S N P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.4 99.5 95.5 N.A. 92.8 93.1 N.A. N.A. 20.8 20.6 40.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 36.4 99.6 96.5 N.A. 96 96 N.A. N.A. 38 38 51.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 93.3 N.A. N.A. 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. N.A. 20 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 12 0 0 0 0 67 12 12 56 0 0 0 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 12 0 12 0 0 0 0 0 0 12 23 % D
% Glu: 67 0 12 0 12 0 0 12 12 0 12 12 12 0 0 % E
% Phe: 0 0 0 12 0 0 0 12 0 56 0 0 0 12 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 0 0 12 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 0 0 56 0 0 12 0 0 0 0 0 0 0 56 12 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 12 0 0 0 0 0 12 12 0 34 % N
% Pro: 0 0 0 23 56 56 12 12 0 0 12 0 0 12 12 % P
% Gln: 0 56 0 0 0 0 0 0 0 0 67 0 0 0 12 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 12 0 12 12 67 12 23 0 0 23 12 0 0 % S
% Thr: 12 23 0 56 0 0 0 56 0 12 0 0 12 0 0 % T
% Val: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 0 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _