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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS4
All Species:
16.97
Human Site:
S400
Identified Species:
46.67
UniProt:
Q8IUM7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUM7
NP_849195.2
802
87117
S400
P
S
K
E
L
D
F
S
Y
L
T
F
P
S
G
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
A371
M
T
D
N
R
K
G
A
K
S
R
L
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001110331
802
87107
S400
P
S
K
E
L
D
F
S
Y
L
T
F
P
S
G
Dog
Lupus familis
XP_540832
800
86767
S398
S
Q
K
E
L
G
F
S
Y
L
A
F
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGD7
802
87267
S400
P
S
K
E
L
D
F
S
Y
L
P
F
P
A
R
Rat
Rattus norvegicus
Q8CJH6
802
87299
S400
P
S
K
E
L
D
F
S
Y
L
P
F
P
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YIB9
811
90524
D412
G
D
T
I
I
S
L
D
F
S
S
N
E
S
D
Frog
Xenopus laevis
Q9I8A9
805
90946
S385
E
L
N
E
E
N
N
S
E
C
L
F
D
K
L
Zebra Danio
Brachydanio rerio
Q1ECW2
933
100083
V417
S
S
M
E
P
A
Q
V
E
S
G
P
R
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.4
99.5
95.5
N.A.
92.8
93.1
N.A.
N.A.
20.8
20.6
40.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.4
99.6
96.5
N.A.
96
96
N.A.
N.A.
38
38
51.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
80
80
N.A.
N.A.
6.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
26.6
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
12
0
0
12
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
12
12
0
0
45
0
12
0
0
0
0
12
0
12
% D
% Glu:
12
0
0
78
12
0
0
0
23
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
56
0
12
0
0
67
0
0
0
% F
% Gly:
12
0
0
0
0
12
12
0
0
0
12
0
0
0
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
56
0
0
12
0
0
12
0
0
0
0
12
0
% K
% Leu:
0
12
0
0
56
0
12
0
0
56
12
12
0
0
12
% L
% Met:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
12
0
12
12
0
0
0
0
12
0
0
0
% N
% Pro:
45
0
0
0
12
0
0
0
0
0
23
12
56
0
0
% P
% Gln:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
12
0
12
0
23
% R
% Ser:
23
56
0
0
0
12
0
67
0
34
12
0
12
67
23
% S
% Thr:
0
12
12
0
0
0
0
0
0
0
23
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
56
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _