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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WFDC3
All Species:
1.21
Human Site:
S224
Identified Species:
3.81
UniProt:
Q8IUB2
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUB2
NP_542181.1
231
24687
S224
N
W
T
V
R
S
D
S
E
L
E
I
P
V
P
Chimpanzee
Pan troglodytes
A4K2N9
123
13294
Rhesus Macaque
Macaca mulatta
A4K2T2
123
13376
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97430
131
14290
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Q9N0L8
191
21115
S182
F
P
E
E
Y
E
A
S
Q
D
E
S
T
L
L
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084488
167
18504
D160
Q
K
C
C
Q
S
G
D
E
Q
K
C
M
H
L
Zebra Danio
Brachydanio rerio
XP_684531
168
17761
G161
K
C
C
P
T
T
C
G
H
A
C
D
D
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202083
210
21458
R203
D
P
S
P
V
F
S
R
P
L
N
D
M
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.2
24.2
N.A.
N.A.
25.5
N.A.
26.4
N.A.
N.A.
22.5
25.9
N.A.
N.A.
N.A.
N.A.
32.4
Protein Similarity:
100
32
31.6
N.A.
N.A.
35
N.A.
39.8
N.A.
N.A.
32.9
32
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
100
0
0
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
0
0
N.A.
N.A.
0
N.A.
26.6
N.A.
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
13
0
0
13
0
0
0
0
0
% A
% Cys:
0
13
25
13
0
0
13
0
0
0
13
13
0
0
13
% C
% Asp:
13
0
0
0
0
0
13
13
0
13
0
25
13
0
0
% D
% Glu:
0
0
13
13
0
13
0
0
25
0
25
0
0
0
0
% E
% Phe:
13
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
13
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
13
13
0
0
0
0
0
0
0
0
13
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
25
0
0
0
25
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
25
0
25
0
0
0
0
13
0
0
0
13
13
13
% P
% Gln:
13
0
0
0
13
0
0
0
13
13
0
0
0
0
0
% Q
% Arg:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
13
% R
% Ser:
0
0
13
0
0
25
13
25
0
0
0
13
0
0
0
% S
% Thr:
0
0
13
0
13
13
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
13
13
0
0
0
0
0
0
0
0
13
0
% V
% Trp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _