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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC125
All Species:
11.82
Human Site:
T345
Identified Species:
28.89
UniProt:
Q86Z20
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z20
NP_789786.2
511
58629
T345
N
D
Q
A
L
Q
L
T
Q
M
D
K
M
H
K
Chimpanzee
Pan troglodytes
P61584
1003
117506
T478
E
F
E
L
A
Q
L
T
K
Q
Y
R
G
N
E
Rhesus Macaque
Macaca mulatta
XP_001092742
277
31349
K130
W
M
N
W
K
H
L
K
E
D
G
F
P
S
P
Dog
Lupus familis
XP_544367
510
57675
T344
N
D
Q
A
L
R
L
T
Q
M
D
K
M
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5U465
500
56593
L333
K
N
E
Q
A
L
R
L
A
G
G
D
L
C
K
Rat
Rattus norvegicus
NP_001128233
508
57304
L340
K
N
D
Q
A
L
R
L
A
R
G
D
V
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512347
540
61498
T342
N
D
Q
I
L
R
L
T
Q
L
D
N
I
C
K
Chicken
Gallus gallus
XP_424893
508
56771
L331
R
K
D
Q
A
L
R
L
A
E
V
I
K
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGP7
465
53808
R311
R
V
G
E
N
V
L
R
Q
A
E
T
D
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798286
493
55563
Y345
N
E
H
L
Q
E
A
Y
L
V
A
D
A
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.1
50.8
74.7
N.A.
71.8
70.4
N.A.
52.5
52.2
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
100
32.2
52.2
86.3
N.A.
82.3
82.5
N.A.
65.9
67.7
N.A.
54.9
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
20
6.6
86.6
N.A.
6.6
0
N.A.
60
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
53.3
13.3
93.3
N.A.
26.6
20
N.A.
80
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
40
0
10
0
30
10
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% C
% Asp:
0
30
20
0
0
0
0
0
0
10
30
30
10
0
0
% D
% Glu:
10
10
20
10
0
10
0
0
10
10
10
0
0
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
30
0
10
0
0
% G
% His:
0
0
10
0
0
10
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
10
10
10
0
% I
% Lys:
20
10
0
0
10
0
0
10
10
0
0
20
10
0
50
% K
% Leu:
0
0
0
20
30
30
60
30
10
10
0
0
10
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
20
0
0
20
0
0
% M
% Asn:
40
20
10
0
10
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% P
% Gln:
0
0
30
30
10
20
0
0
40
10
0
0
0
0
0
% Q
% Arg:
20
0
0
0
0
20
30
10
0
10
0
10
0
10
20
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
0
10
0
0
0
% T
% Val:
0
10
0
0
0
10
0
0
0
10
10
0
10
0
0
% V
% Trp:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _