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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC125
All Species:
26.67
Human Site:
S425
Identified Species:
65.19
UniProt:
Q86Z20
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z20
NP_789786.2
511
58629
S425
L
A
H
Q
R
K
V
S
Y
M
L
A
R
A
L
Chimpanzee
Pan troglodytes
P61584
1003
117506
N709
V
K
H
Q
K
E
L
N
D
M
Q
A
Q
L
V
Rhesus Macaque
Macaca mulatta
XP_001092742
277
31349
E199
Y
M
L
A
R
A
L
E
D
K
D
T
A
S
K
Dog
Lupus familis
XP_544367
510
57675
S424
L
A
H
Q
R
K
V
S
Y
M
L
A
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5U465
500
56593
S413
L
A
H
Q
R
K
V
S
Y
M
L
A
R
A
L
Rat
Rattus norvegicus
NP_001128233
508
57304
S420
L
A
H
Q
R
K
V
S
Y
M
L
A
R
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512347
540
61498
S422
L
A
H
Q
R
K
V
S
Y
M
L
A
R
A
V
Chicken
Gallus gallus
XP_424893
508
56771
S411
L
A
H
Q
R
K
V
S
Y
M
L
A
R
A
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGP7
465
53808
S380
L
A
H
Q
R
K
V
S
Y
M
L
A
R
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798286
493
55563
L415
R
E
D
V
G
Q
L
L
A
E
T
M
D
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.1
50.8
74.7
N.A.
71.8
70.4
N.A.
52.5
52.2
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
100
32.2
52.2
86.3
N.A.
82.3
82.5
N.A.
65.9
67.7
N.A.
54.9
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
26.6
6.6
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
73.3
20
100
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
10
0
10
0
0
10
0
0
80
10
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
20
0
10
0
10
0
0
% D
% Glu:
0
10
0
0
0
10
0
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
0
0
10
70
0
0
0
10
0
0
0
0
10
% K
% Leu:
70
0
10
0
0
0
30
10
0
0
70
0
0
10
40
% L
% Met:
0
10
0
0
0
0
0
0
0
80
0
10
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
80
0
10
0
0
0
0
10
0
10
0
10
% Q
% Arg:
10
0
0
0
80
0
0
0
0
0
0
0
70
0
0
% R
% Ser:
0
0
0
0
0
0
0
70
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% T
% Val:
10
0
0
10
0
0
70
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _