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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYLK4
All Species:
13.33
Human Site:
S353
Identified Species:
48.89
UniProt:
Q86YV6
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YV6
NP_001012418.2
388
44508
S353
K
S
W
R
I
S
A
S
E
A
L
K
H
P
W
Chimpanzee
Pan troglodytes
XP_527218
388
44535
S353
K
S
W
R
I
S
A
S
E
A
L
K
H
P
W
Rhesus Macaque
Macaca mulatta
XP_001090801
385
44225
I350
I
K
E
K
S
W
R
I
S
A
S
E
A
L
K
Dog
Lupus familis
XP_545312
405
46460
S354
K
S
W
R
I
S
A
S
E
A
L
K
H
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUV5
386
43887
I350
I
K
E
K
S
W
R
I
S
A
S
E
A
L
K
Rat
Rattus norvegicus
P20689
610
65798
E546
Q
S
A
R
M
S
A
E
Q
C
L
A
H
P
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510079
521
59040
S473
K
C
W
R
I
S
A
S
E
A
L
K
H
P
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.9
83.4
N.A.
84.7
37.5
N.A.
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.1
87.6
N.A.
90.7
48.3
N.A.
66.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
6.6
53.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
20
73.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
72
0
0
86
0
15
29
0
0
% A
% Cys:
0
15
0
0
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
29
0
0
0
0
15
58
0
0
29
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% H
% Ile:
29
0
0
0
58
0
0
29
0
0
0
0
0
0
0
% I
% Lys:
58
29
0
29
0
0
0
0
0
0
0
58
0
0
29
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
72
0
0
29
0
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% P
% Gln:
15
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
0
0
0
72
0
0
29
0
0
0
0
0
0
0
0
% R
% Ser:
0
58
0
0
29
72
0
58
29
0
29
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
58
0
0
29
0
0
0
0
0
0
0
0
72
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _