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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK223 All Species: 9.09
Human Site: S737 Identified Species: 25
UniProt: Q86YV5 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YV5 NP_001074295 1406 149688 S737 S S D L E K V S Q G S A E S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094718 1322 141203 S731 S T E D V S P S G P R Q P P P
Dog Lupus familis XP_540000 1393 147853 S707 S S D L E K V S Q G S A E S L
Cat Felis silvestris
Mouse Mus musculus Q571I4 1179 126621 P620 F F W T Q G S P K P R T A S P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507039 1758 193149 S1072 R I P S P R V S R A A L L K Q
Chicken Gallus gallus XP_420588 1313 142360 S730 H S S E P N H S P P P A E S L
Frog Xenopus laevis NP_001082542 1282 142382 K712 G K K K H F T K I L S L D S G
Zebra Danio Brachydanio rerio XP_001921602 1695 184654 A1033 P A S C P P P A S P T S N S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177956 680 74357 D121 Q D E D N S E D P A P L Q K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.4 81.2 N.A. 66.4 N.A. N.A. 24.3 49.9 42.2 27.6 N.A. N.A. N.A. N.A. 21.3
Protein Similarity: 100 N.A. 89.4 85.6 N.A. 70.7 N.A. N.A. 38.5 60.3 55.3 41.1 N.A. N.A. N.A. N.A. 31.2
P-Site Identity: 100 N.A. 13.3 100 N.A. 6.6 N.A. N.A. 13.3 40 13.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. 26.6 100 N.A. 20 N.A. N.A. 33.3 40 20 33.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 12 0 23 12 34 12 0 0 % A
% Cys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 23 23 0 0 0 12 0 0 0 0 12 0 0 % D
% Glu: 0 0 23 12 23 0 12 0 0 0 0 0 34 0 0 % E
% Phe: 12 12 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 0 0 0 0 12 0 0 12 23 0 0 0 0 12 % G
% His: 12 0 0 0 12 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 12 12 12 0 23 0 12 12 0 0 0 0 23 0 % K
% Leu: 0 0 0 23 0 0 0 0 0 12 0 34 12 0 34 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 12 0 0 0 0 0 0 12 0 0 % N
% Pro: 12 0 12 0 34 12 23 12 23 45 23 0 12 12 23 % P
% Gln: 12 0 0 0 12 0 0 0 23 0 0 12 12 0 12 % Q
% Arg: 12 0 0 0 0 12 0 0 12 0 23 0 0 0 0 % R
% Ser: 34 34 23 12 0 23 12 56 12 0 34 12 0 67 23 % S
% Thr: 0 12 0 12 0 0 12 0 0 0 12 12 0 0 0 % T
% Val: 0 0 0 0 12 0 34 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _