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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCF2L2
All Species:
18.79
Human Site:
S522
Identified Species:
45.93
UniProt:
Q86YR7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YR7
NP_055893.2
1114
126963
S522
I
F
H
K
R
Q
V
S
L
M
K
L
A
A
K
Chimpanzee
Pan troglodytes
XP_509745
1123
126012
S510
K
V
F
Q
K
Q
A
S
M
E
E
V
F
H
R
Rhesus Macaque
Macaca mulatta
XP_001103476
1325
144488
S521
V
F
H
R
R
Q
A
S
L
K
K
L
A
A
R
Dog
Lupus familis
XP_535818
1248
142625
I564
K
L
C
D
V
Q
E
I
F
H
K
R
Q
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64096
1149
129131
S542
K
V
F
Q
K
Q
E
S
T
E
E
M
F
H
R
Rat
Rattus norvegicus
Q63406
1149
129391
S553
M
F
H
R
R
Q
A
S
L
K
K
L
A
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515228
1441
162747
S609
K
V
F
Q
K
Q
E
S
M
E
E
M
F
Q
K
Chicken
Gallus gallus
XP_422768
1122
127054
E562
Q
R
I
L
Q
K
L
E
D
V
Q
E
M
F
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922183
1311
148260
S623
M
F
E
K
R
R
V
S
L
K
K
L
A
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392741
1340
152741
I771
L
Q
E
L
Q
E
L
I
E
A
A
E
E
F
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.2
32.7
71.6
N.A.
41.5
42.2
N.A.
34.4
53.3
N.A.
31.1
N.A.
N.A.
22.6
N.A.
N.A.
Protein Similarity:
100
61.1
49.8
78.2
N.A.
60.3
61.5
N.A.
49.4
68
N.A.
49.1
N.A.
N.A.
41.1
N.A.
N.A.
P-Site Identity:
100
13.3
66.6
13.3
N.A.
13.3
73.3
N.A.
20
0
N.A.
73.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
53.3
86.6
13.3
N.A.
46.6
86.6
N.A.
53.3
33.3
N.A.
86.6
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
30
0
0
10
10
0
40
40
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
20
0
0
10
30
10
10
30
30
20
10
0
0
% E
% Phe:
0
40
30
0
0
0
0
0
10
0
0
0
30
20
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
30
0
0
0
0
0
0
10
0
0
0
20
10
% H
% Ile:
10
0
10
0
0
0
0
20
0
0
0
0
0
0
0
% I
% Lys:
40
0
0
20
30
10
0
0
0
30
50
0
0
0
40
% K
% Leu:
10
10
0
20
0
0
20
0
40
0
0
40
0
0
0
% L
% Met:
20
0
0
0
0
0
0
0
20
10
0
20
10
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
30
20
70
0
0
0
0
10
0
10
10
0
% Q
% Arg:
0
10
0
20
40
10
0
0
0
0
0
10
0
0
30
% R
% Ser:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
10
30
0
0
10
0
20
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _