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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF130
All Species:
19.7
Human Site:
T375
Identified Species:
43.33
UniProt:
Q86XS8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XS8
NP_060904.2
419
46405
T375
D
G
E
L
T
P
R
T
G
E
I
N
I
A
V
Chimpanzee
Pan troglodytes
XP_001143540
558
60027
T514
D
G
E
L
T
P
R
T
G
E
I
N
I
A
V
Rhesus Macaque
Macaca mulatta
XP_001106945
400
42977
S358
D
D
G
S
D
E
S
S
P
P
S
A
S
P
A
Dog
Lupus familis
XP_531881
235
26353
E193
E
L
T
P
R
T
G
E
I
N
I
A
V
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM1
419
46357
T375
D
G
E
L
T
P
R
T
G
E
I
N
I
A
V
Rat
Rattus norvegicus
Q6Y290
419
46430
T375
D
G
E
L
T
P
R
T
G
E
I
N
I
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507054
477
53581
T433
D
G
E
L
T
P
R
T
G
E
I
N
I
A
V
Chicken
Gallus gallus
Q90972
381
42801
S339
H
Q
N
M
T
E
S
S
E
Y
E
E
D
D
N
Frog
Xenopus laevis
Q6NRX0
397
43453
P355
R
S
E
G
N
N
L
P
S
S
S
T
G
S
S
Zebra Danio
Brachydanio rerio
Q566M8
419
46332
L372
G
G
L
P
Q
V
L
L
D
S
E
P
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06003
461
52604
P415
G
A
R
E
M
L
F
P
C
R
I
P
E
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75
39.8
55.3
N.A.
98
98
N.A.
65.4
21
39.3
46.7
N.A.
32.3
N.A.
N.A.
N.A.
Protein Similarity:
100
75
56.5
55.6
N.A.
99
98.8
N.A.
71
39.1
55.1
61.3
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
100
100
N.A.
100
6.6
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
100
100
N.A.
100
20
13.3
20
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
19
0
46
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
55
10
0
0
10
0
0
0
10
0
0
0
10
10
0
% D
% Glu:
10
0
55
10
0
19
0
10
10
46
19
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
19
55
10
10
0
0
10
0
46
0
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
64
0
46
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
10
46
0
10
19
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
10
0
0
0
10
0
46
0
0
10
% N
% Pro:
0
0
0
19
0
46
0
19
10
10
0
19
0
10
0
% P
% Gln:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
10
0
10
0
46
0
0
10
0
0
0
10
0
% R
% Ser:
0
10
0
10
0
0
19
19
10
19
19
0
10
19
19
% S
% Thr:
0
0
10
0
55
10
0
46
0
0
0
10
0
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _