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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEP57 All Species: 24.55
Human Site: S264 Identified Species: 54
UniProt: Q86XR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XR8 NP_055494.2 500 57089 S264 R R I K K K K S K P P E K K S
Chimpanzee Pan troglodytes XP_001145217 500 56971 S264 R R I K K K K S K P P E K K S
Rhesus Macaque Macaca mulatta XP_001093565 499 56751 S264 R R I K K K K S K P P E K K S
Dog Lupus familis XP_533972 501 57208 S264 R R V K K K K S K P P E K K S
Cat Felis silvestris
Mouse Mus musculus Q8CEE0 500 56891 S265 R K I K K K K S K P P E K K G
Rat Rattus norvegicus B4F7A7 499 57022 S265 R K I K K K K S K P P E K K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511190 512 58704 K271 R I K K K K T K T K Q S D K K
Chicken Gallus gallus XP_417188 497 56836 K258 R K P R K K T K Q P E K K C S
Frog Xenopus laevis Q5FWP9 488 55089 S249 K V K K K K Q S K Q K N A I S
Zebra Danio Brachydanio rerio NP_001074152 440 49270 P234 I Q S V S P R P H K S S K I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790540 519 58520 K282 T E E R R P R K V K K K R K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97 90.4 N.A. 87.8 86 N.A. 64 60.7 36.2 40.5 N.A. N.A. N.A. N.A. 36.6
Protein Similarity: 100 99.8 97.5 94.2 N.A. 91.8 91.4 N.A. 77.3 74.5 57.2 57.5 N.A. N.A. N.A. N.A. 58
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 33.3 40 40 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 33.3 66.6 53.3 20 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 10 10 0 0 0 0 0 0 0 10 55 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 10 10 46 0 0 0 0 0 0 0 0 0 0 19 0 % I
% Lys: 10 28 19 73 82 82 55 28 64 28 19 19 73 73 28 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 10 0 0 19 0 10 0 64 55 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 10 0 10 10 10 0 0 0 0 % Q
% Arg: 73 37 0 19 10 0 19 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 10 0 10 0 0 64 0 0 10 19 0 0 55 % S
% Thr: 10 0 0 0 0 0 19 0 10 0 0 0 0 0 0 % T
% Val: 0 10 10 10 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _