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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR5A
All Species:
12.42
Human Site:
S41
Identified Species:
39.05
UniProt:
Q86XA9
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XA9
NP_056288.1
2040
222004
S41
E
K
L
L
L
A
T
S
R
N
D
V
R
E
K
Chimpanzee
Pan troglodytes
XP_522993
2045
222704
S41
E
K
L
L
L
A
T
S
R
N
D
V
R
E
K
Rhesus Macaque
Macaca mulatta
XP_001108090
2090
225671
R56
T
P
A
R
V
G
A
R
W
L
G
G
Q
L
V
Dog
Lupus familis
XP_537407
2046
222479
S41
E
K
L
L
L
A
T
S
K
S
D
V
K
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5PRF0
2038
219803
N41
E
K
L
L
L
A
T
N
R
E
D
V
R
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421228
2046
223434
S41
E
K
L
L
P
V
T
S
R
T
D
I
K
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q8JFV4
1998
216687
D41
K
K
L
L
P
A
T
D
R
A
D
V
K
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780534
2231
242741
N193
D
K
V
L
I
A
A
N
R
S
D
I
K
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
86.5
92.1
N.A.
87.2
N.A.
N.A.
N.A.
79.6
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
45.9
Protein Similarity:
100
99.2
88.1
95.9
N.A.
93.2
N.A.
N.A.
N.A.
88.9
N.A.
76.9
N.A.
N.A.
N.A.
N.A.
64.9
P-Site Identity:
100
100
0
80
N.A.
86.6
N.A.
N.A.
N.A.
60
N.A.
60
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
N.A.
N.A.
N.A.
73.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
75
25
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
13
0
0
88
0
0
0
0
% D
% Glu:
63
0
0
0
0
0
0
0
0
13
0
0
0
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
0
0
0
0
13
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
25
0
0
0
% I
% Lys:
13
88
0
0
0
0
0
0
13
0
0
0
50
0
63
% K
% Leu:
0
0
75
88
50
0
0
0
0
13
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
0
25
0
0
0
0
13
% N
% Pro:
0
13
0
0
25
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% Q
% Arg:
0
0
0
13
0
0
0
13
75
0
0
0
38
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
25
0
0
0
0
13
% S
% Thr:
13
0
0
0
0
0
75
0
0
13
0
0
0
0
0
% T
% Val:
0
0
13
0
13
13
0
0
0
0
0
63
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _