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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR5A
All Species:
4.55
Human Site:
S220
Identified Species:
14.29
UniProt:
Q86XA9
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XA9
NP_056288.1
2040
222004
S220
V
A
T
L
C
F
K
S
F
E
G
S
N
Y
D
Chimpanzee
Pan troglodytes
XP_522993
2045
222704
K225
S
V
A
T
L
C
F
K
S
F
E
G
S
N
Y
Rhesus Macaque
Macaca mulatta
XP_001108090
2090
225671
E264
V
E
S
N
D
V
R
E
K
Q
K
T
L
V
E
Dog
Lupus familis
XP_537407
2046
222479
S226
V
A
T
L
C
F
K
S
F
E
G
S
N
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5PRF0
2038
219803
K225
S
V
A
T
L
C
F
K
S
F
E
G
S
N
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421228
2046
223434
K225
S
V
V
T
L
C
F
K
S
F
E
G
S
N
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q8JFV4
1998
216687
F224
D
N
V
A
T
L
C
F
R
A
L
E
G
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780534
2231
242741
R377
N
I
V
S
S
S
F
R
A
L
D
G
S
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
86.5
92.1
N.A.
87.2
N.A.
N.A.
N.A.
79.6
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
45.9
Protein Similarity:
100
99.2
88.1
95.9
N.A.
93.2
N.A.
N.A.
N.A.
88.9
N.A.
76.9
N.A.
N.A.
N.A.
N.A.
64.9
P-Site Identity:
100
0
6.6
100
N.A.
0
N.A.
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
40
100
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
25
13
0
0
0
0
13
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
25
38
13
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
13
0
0
0
0
0
13
0
0
0
25
% D
% Glu:
0
13
0
0
0
0
0
13
0
25
38
13
0
0
13
% E
% Phe:
0
0
0
0
0
25
50
13
25
38
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
25
50
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
25
38
13
0
13
0
0
0
0
% K
% Leu:
0
0
0
25
38
13
0
0
0
13
13
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
13
0
13
0
0
0
0
0
0
0
0
25
50
13
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
13
13
13
0
0
0
0
0
0
% R
% Ser:
38
0
13
13
13
13
0
25
38
0
0
25
50
13
0
% S
% Thr:
0
0
25
38
13
0
0
0
0
0
0
13
0
0
0
% T
% Val:
38
38
38
0
0
13
0
0
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _