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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR5A
All Species:
21.52
Human Site:
S1255
Identified Species:
67.62
UniProt:
Q86XA9
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XA9
NP_056288.1
2040
222004
S1255
Q
E
M
K
K
R
D
S
R
N
D
F
L
V
L
Chimpanzee
Pan troglodytes
XP_522993
2045
222704
S1260
Q
E
M
K
K
R
D
S
R
N
D
F
L
V
L
Rhesus Macaque
Macaca mulatta
XP_001108090
2090
225671
A1308
L
L
R
R
A
V
L
A
C
L
R
Q
L
V
Q
Dog
Lupus familis
XP_537407
2046
222479
S1261
Q
E
M
K
K
R
D
S
R
N
D
F
L
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5PRF0
2038
219803
S1256
Q
E
M
K
K
R
D
S
R
N
D
F
L
V
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421228
2046
223434
S1260
Q
E
R
K
Q
R
D
S
R
D
D
F
L
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q8JFV4
1998
216687
E1220
A
Q
E
Q
R
L
H
E
S
T
D
F
L
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780534
2231
242741
T1437
R
E
M
R
V
K
T
T
T
N
N
Y
L
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
86.5
92.1
N.A.
87.2
N.A.
N.A.
N.A.
79.6
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
45.9
Protein Similarity:
100
99.2
88.1
95.9
N.A.
93.2
N.A.
N.A.
N.A.
88.9
N.A.
76.9
N.A.
N.A.
N.A.
N.A.
64.9
P-Site Identity:
100
100
13.3
100
N.A.
100
N.A.
N.A.
N.A.
80
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
26.6
100
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
63
0
0
13
75
0
0
0
0
% D
% Glu:
0
75
13
0
0
0
0
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
63
50
13
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
13
0
0
0
13
13
0
0
13
0
0
100
0
88
% L
% Met:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
63
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
63
13
0
13
13
0
0
0
0
0
0
13
0
0
13
% Q
% Arg:
13
0
25
25
13
63
0
0
63
0
13
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
63
13
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
13
13
13
13
0
0
0
0
0
% T
% Val:
0
0
0
0
13
13
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _