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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIR1
All Species:
27.27
Human Site:
S196
Identified Species:
54.55
UniProt:
Q86X95
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X95
NP_004873.3
450
52313
S196
N
L
T
A
N
D
P
S
Q
E
Y
V
A
S
E
Chimpanzee
Pan troglodytes
XP_001148591
450
52340
S196
N
L
T
A
N
D
P
S
Q
E
Y
V
A
S
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535968
475
55209
S196
N
L
T
A
N
D
P
S
Q
E
Y
V
A
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DA19
450
51819
S196
N
L
T
A
N
D
P
S
Q
D
Y
V
A
S
D
Rat
Rattus norvegicus
Q5U2T8
451
51398
S196
N
L
T
A
N
D
P
S
Q
D
Y
V
A
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514863
861
95412
S196
N
L
T
A
N
D
P
S
Q
E
Y
V
A
S
E
Chicken
Gallus gallus
Q5ZI03
460
53359
S194
N
L
T
A
N
D
P
S
Q
E
F
V
A
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689017
177
20337
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649072
366
43629
W134
R
C
L
K
C
H
K
W
G
H
I
N
T
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491654
560
65813
L227
G
M
Q
T
D
Q
Q
L
T
R
M
K
K
E
M
Sea Urchin
Strong. purpuratus
XP_794696
488
58217
N185
K
V
N
G
Q
A
K
N
Q
R
F
V
G
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZ67
595
69129
N237
L
K
D
A
V
M
P
N
E
E
L
R
L
K
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
84
N.A.
80.2
80.2
N.A.
43.5
70
N.A.
33.3
N.A.
38.4
N.A.
36.4
41.3
Protein Similarity:
100
99.5
N.A.
89.4
N.A.
86
86.6
N.A.
48.3
81.5
N.A.
36.6
N.A.
52.4
N.A.
51.2
56.5
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
100
93.3
N.A.
0
N.A.
0
N.A.
0
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
0
N.A.
6.6
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
9
0
0
0
0
0
0
59
0
0
% A
% Cys:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
59
0
0
0
17
0
0
0
9
17
% D
% Glu:
0
0
0
0
0
0
0
0
9
50
0
0
0
9
42
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
9
0
0
9
0
0
0
0
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
9
9
0
9
0
0
17
0
0
0
0
9
9
9
9
% K
% Leu:
9
59
9
0
0
0
0
9
0
0
9
0
9
0
0
% L
% Met:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
9
% M
% Asn:
59
0
9
0
59
0
0
17
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
9
9
9
0
67
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
17
0
9
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
59
0
0
0
0
0
67
9
% S
% Thr:
0
0
59
9
0
0
0
0
9
0
0
0
9
0
0
% T
% Val:
0
9
0
0
9
0
0
0
0
0
0
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _