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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FCHSD1 All Species: 21.82
Human Site: S175 Identified Species: 53.33
UniProt: Q86WN1 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WN1 NP_258260.1 690 76942 S175 V Q A R L N R S D H G I F H S
Chimpanzee Pan troglodytes XP_517998 708 78893 S193 V Q A R L N R S D H G I F H S
Rhesus Macaque Macaca mulatta XP_001089589 683 76013 S229 V Q A R L N R S D H G I F H S
Dog Lupus familis XP_544315 692 76848 S175 V Q A R L N R S D H G L F H T
Cat Felis silvestris
Mouse Mus musculus Q6PFY1 688 76237 S173 V Q A R L N R S D H G I F H S
Rat Rattus norvegicus NP_001103351 690 76749 N175 V Q A R L N R N D H G I F H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517286 382 42400
Chicken Gallus gallus XP_425188 790 86565 S254 V E A R L R K S D R R I F H T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648290 795 89574 K182 I E E K L K K K K G S F F Q S
Honey Bee Apis mellifera XP_392840 975 109344 K182 I E E K L K K K K G S F F Q S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.9 88.5 91 N.A. 91 90.7 N.A. 38.9 43.4 N.A. N.A. N.A. 25.6 25.1 N.A. N.A.
Protein Similarity: 100 86.4 89.4 93.2 N.A. 93.4 93.7 N.A. 45.2 57.5 N.A. N.A. N.A. 44.9 40.9 N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 93.3 N.A. 0 60 N.A. N.A. N.A. 20 20 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 80 N.A. N.A. N.A. 46.6 46.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 % D
% Glu: 0 30 20 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 20 90 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 20 60 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 60 0 0 0 70 0 % H
% Ile: 20 0 0 0 0 0 0 0 0 0 0 60 0 0 0 % I
% Lys: 0 0 0 20 0 20 30 20 20 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 90 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 60 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 60 0 0 0 0 0 0 0 0 0 0 0 20 0 % Q
% Arg: 0 0 0 70 0 10 60 0 0 10 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 60 0 0 20 0 0 0 70 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % T
% Val: 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _